Vaccine-associated enhanced disease and pathogenic human coronaviruses

C Gartlan, T Tipton, FJ Salguero, Q Sattentau… - Frontiers in …, 2022 - frontiersin.org
Vaccine-associated enhanced disease (VAED) is a difficult phenomenon to define and can
be confused with vaccine failure. Using studies on respiratory syncytial virus (RSV) …

Platelets and SARS-CoV-2 during COVID-19: immunity, thrombosis, and beyond

A Sciaudone, H Corkrey, F Humphries… - Circulation …, 2023 - Am Heart Assoc
COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase
mortality in patients. Platelets are fast responders to pathogen presence, alerting the …

Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses

F Hellgren, A Cagigi, R Arcoverde Cerveira… - Nature …, 2023 - nature.com
Licensed rabies virus vaccines based on whole inactivated virus are effective in humans.
However, there is a lack of detailed investigations of the elicited immune response, and …

Three-dimensional visualization of viral structure, entry, and replication underlying the spread of SARS-CoV-2

JW Saville, AM Berezuk, SS Srivastava… - Chemical …, 2022 - ACS Publications
The global spread of SARS-CoV-2 has proceeded at an unprecedented rate. Remarkably,
characterization of the virus using modern tools in structural biology has also progressed at …

[HTML][HTML] Metformin suppresses SARS-CoV-2 in cell culture

H Parthasarathy, D Tandel, AH Siddiqui, KH Harshan - Virus research, 2023 - Elsevier
Comorbidities such as diabetes worsen COVID-19 severity and recovery. Metformin, a first-
line medication for type 2 diabetes, has antiviral properties and certain studies have also …

Pilot findings on SARS-CoV-2 vaccine-induced pituitary diseases: a mini review from diagnosis to pathophysiology

A Taieb, EE Mounira - Vaccines, 2022 - mdpi.com
Since the emergence of the COVID-19 pandemic at the end of 2019, a massive vaccination
campaign has been undertaken rapidly and worldwide. Like other vaccines, the COVID-19 …

Differential neutralizing antibody responses elicited by CoronaVac and BNT162b2 against SARS-CoV-2 Lambda in Chile

ML Acevedo, A Gaete-Argel, L Alonso-Palomares… - Nature …, 2022 - nature.com
SARS-CoV-2 variant Lambda was dominant in several South American countries, including
Chile. To ascertain the efficacy of local vaccination efforts, we used pseudotyped viruses to …

Comparison of viral inactivation methods on the characteristics of extracellular vesicles from SARS‐CoV‐2 infected human lung epithelial cells

S Kongsomros, N Pongsakul… - Journal of …, 2022 - Wiley Online Library
The interaction of SARS‐CoV‐2 infection with extracellular vesicles (EVs) is of particular
interest at the moment. Studying SARS‐CoV‐2 contaminated‐EV isolates in instruments …

Multipolymer microsphere delivery of SARS-CoV-2 antigens

F Shahjin, M Patel, J Machhi, JD Cohen, MU Nayan… - Acta Biomaterialia, 2023 - Elsevier
Effective antigen delivery facilitates antiviral vaccine success defined by effective immune
protective responses against viral exposures. To improve severe acute respiratory syndrome …

SARS-CoV-2 variant delta potently suppresses innate immune response and evades interferon-activated antiviral responses in human colon epithelial cells

D Tandel, V Sah, NK Singh, PS Potharaju… - Microbiology …, 2022 - Am Soc Microbiol
The Delta variant of SARS-CoV-2 has caused more severe infections than its previous
variants. We studied the host innate immune response to Delta, Alpha, and two earlier …