Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on
the development of its pathophysiologic characteristics over time, and how these time …

Since its inception in late December 2020 in China, novel coronavirus has affected the
global socio-economic aspect. Currently, the world is seeking safe and effective treatment …

Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

Purpose Hypercapnia is frequent during mechanical ventilation for acute respiratory distress
syndrome (ARDS), but its effects on morbidity and mortality are still controversial. We …

Background In COVID-19 patients with acute respiratory distress syndrome (ARDS), the
effectiveness of ventilatory rescue strategies remains uncertain, with controversial efficacy …

Background Inhaled nitric oxide (iNO) is used as rescue therapy in patients with refractory
hypoxemia due to severe COVID-19 acute respiratory distress syndrome (ARDS) despite the …

Nitric oxide (NO) plays an important role in cardiovascular and immune systems.
Quantification of blood nitrite and nitrate, two relatively stable metabolites of NO (generally …

A damaged endothelium is an underlying condition of the many complications of COVID-19
patients. The increased mortality risk associated with diseases that have underlying …