Metabolic engineering: methodologies and applications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …
through the genetic manipulation of microbial metabolism. While the discipline is a little over …
Microbial production of advanced biofuels
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
Synthetic biology: bottom-up assembly of molecular systems
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …
opportunities to engineer artificial vesicular systems for applications with previously unmet …
Metabolic engineering of Escherichia coli for natural product biosynthesis
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
INTRODUCTION To combat invading pathogens, cells develop an adaptive immune
response by changing their own genetic information. In vertebrates, the generation of …
response by changing their own genetic information. In vertebrates, the generation of …
Synthetic biology strategies for microbial biosynthesis of plant natural products
Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
Synthetic protein condensates for cellular and metabolic engineering
Protein condensates are distinct structures assembled in living cells that concentrate
molecules via phase separation in a confined subcellular compartment. In the past decade …
molecules via phase separation in a confined subcellular compartment. In the past decade …
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
Multienzymatic cascade reactions via enzyme complex by immobilization
ET Hwang, S Lee - ACS Catalysis, 2019 - ACS Publications
Multienzymatic cascade reactions are a most important technology to succeed in industrial
process development, such as synthesis of pharmaceutical, cosmetic, and nutritional …
process development, such as synthesis of pharmaceutical, cosmetic, and nutritional …
Engineering cellular metabolism
J Nielsen, JD Keasling - Cell, 2016 - cell.com
Metabolic engineering is the science of rewiring the metabolism of cells to enhance
production of native metabolites or to endow cells with the ability to produce new products …
production of native metabolites or to endow cells with the ability to produce new products …