The cardinal stages of macroautophagy are driven by core autophagy‐related (ATG)
proteins, whose ablation largely abolishes intracellular turnover. Disrupting ATG genes is …

Autophagy plays a key role in the maintenance of cellular homeostasis. In healthy cells,
such a homeostatic activity constitutes a robust barrier against malignant transformation …

Autophagy is fundamental to the maintenance of intracellular homeostasis in virtually all
human cells. Accordingly, defective autophagy predisposes healthy cells to undergoing …

A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …

The mammalian target of rapamycin (mTOR) downstream of phosphatidylinositol 3-kinase
(PI3K) in the growth factor receptor (GFR) pathway is a crucial metabolic sensor that …

Human papillomaviruses (HPVs) are small DNA viruses causally associated with benign
warts and multiple cancers, including cervical and head-and-neck cancers. While the vast …

Human papillomaviruses (HPVs) cause a subset of head and neck squamous cell
carcinomas (HNSCCs). Previously, we demonstrated that HPV16 oncogene E6 or E6/E7 …

Autophagy is a highly conserved lysosomal degradation system that involves the creation of
autophagosomes, which eventually fuse with lysosomes and breakdown misfolded proteins …

The broad immunologic roles of autophagy span innate and adaptive immunity and are
often manifested in inflammatory diseases. The immune effects of autophagy partially …

Human papilloma viruses (HPVs) are a group of double-stranded DNA viruses known to be
the primary cause of cervical cancer. In addition, evidence has now established their role in …