Highlights•Multi-drug co-crystals would offer an efficient solution to combat various
diseases.•Cocrystals would play vital role in market due to expanded patent …

Crystal engineering of organic cocrystals is gaining interest across a variety of disciplines.
The solid-state grinding approach to preparing cocrystals is an alternative to the traditional …

A mechanism for cocrystal synthesis is reported whereby nucleation and growth of
cocrystals are directed by the effect of the cocrystal components on reducing the solubility of …

Purpose The purpose of this work was to investigate the mechanisms of cocrystal formation
during cogrinding and storage of solid reactants, and to establish the effects of water by …

A history of cocrystals reported in the literature prior to the year 2000 is presented.
Concentration is on cocrystals that contain only organic components, not including species …

We have extended the established physical stability treatment for hydrates/solvates to co-
crystals with solid co-crystal formers. Based on the proposed treatment, a suspension/slurry …

Co-crystal forming abilities of the two anti-HIV drugs lamivudine and zidovudine were
studied. A study of five crystal structures was carried out to investigate the general …

Despite the great interest that cocrystals are currently gaining for their application to the
design of new supramolecular structures with desired functional properties, studies …

Ten new co-crystals of an antibacterial drug sulfamethazine (SFZ) with various carboxylic
acid and amide co-formers have been synthesized. These new forms are characterized by …

Co-grinding sulfadimidine [4-amino-N-(4, 6-dimethylpyrimidin-2-yl) benzenesulfonamide]
with several aromatic carboxylic acids in the solid state produces 1: 1 hydrogen bonded …