Abstract This Protocol Extension describes the low-cost production of rapidly customizable
optical neural probes for in vivo optogenetics. We detail the use of a 3D printer to fabricate …

IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …

Sex differences have been found in allocentric spatial learning and memory tasks, with the
literature indicating that males outperform females, although this issue is still controversial …

Mice are the most commonly used laboratory animal, yet there are limited studies which
investigate the effects of repeated handling on their welfare and scientific outcomes …

Prenatal stress (PNS) profoundly impacts maternal and offspring health, with enduring
effects including microbiome alterations, neuroinflammation, and behavioral disturbances …

Simple Summary Blood sampling from laboratory animals is a routine procedure in
biomedical research, and husbandry is known to affect the quality of animal models. The …

Evidence has demonstrated the hippocampal cholinergic system and the mammalian target
of rapamycin (mTOR) participation during the memory formation of aversive events. This …

Experiences are linked to emotions impacting memory consolidation and associated brain
neuronal circuits. Posttraumatic stress disorder is an example of strong negative emotions …

Reduced somatostatin (SST) and SST-expressing GABAergic neurons are well-replicated
findings in Alzheimer's disease (AD) and are associated with cognitive deficits. SST cells …

Inflammation, reduced gamma-aminobutyric acidergic (GABAergic) function and altered
neuroplasticity are co-occurring pathophysiologies in major depressive disorder (MDD) …