[HTML][HTML] Cell membrane modulation as adjuvant in cancer therapy

S Zalba, TLM Ten Hagen - Cancer treatment reviews, 2017 - Elsevier
Cancer is a complex disease involving numerous biological processes, which can exist in
parallel, can be complementary, or are engaged when needed and as such can replace …

Molecular mechanisms of drug resistance and its reversal in cancer

M Kartal-Yandim, A Adan-Gokbulut… - Critical reviews in …, 2016 - Taylor & Francis
Chemotherapy is the main strategy for the treatment of cancer. However, the main problem
limiting the success of chemotherapy is the development of multidrug resistance. The …

New insights into targeting membrane lipids for cancer therapy

G Preta - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Modulation of membrane lipid composition and organization is currently developing as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …

Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles

C Peetla, S Vijayaraghavalu, V Labhasetwar - Advanced drug delivery …, 2013 - Elsevier
In this review, we focus on the biophysics of cell membrane lipids, particularly when cancers
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …

Lipidomic landscape in cancer: Actionable insights for membrane‐based therapy and diagnoses

PK Agarwala, R Aneja, S Kapoor - Medicinal Research …, 2022 - Wiley Online Library
Cancer cells display altered cellular lipid metabolism, including disruption in endogenous
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …

Perturbing the dynamics and organization of cell membrane components: a new paradigm for cancer-targeted therapies

N Bernardes, A M. Fialho - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multi-process disease where different mechanisms exist in parallel to ensure
cell survival and constant adaptation to the extracellular environment. To adapt rapidly …

A comprehensive review on natural occurrence, synthesis and biological activities of glycolipids

RCR Jala, S Vudhgiri, CG Kumar - Carbohydrate Research, 2022 - Elsevier
Glycolipids are ubiquitous and biologically important molecules and are involved in diverse
biological functions and exhibit biosurfactant applications due to their surface-active and …

Ceramides and their roles in programmed cell death

MB Pilátová, Z Solárová, R Mezencev… - Advances in Medical …, 2023 - Elsevier
Programmed cell death plays a crucial role in maintaining the homeostasis and integrity of
multicellular organisms, and its dysregulation contributes to the pathogenesis of many …

Emerging roles of ceramides in breast cancer biology and therapy

P Pal, GE Atilla-Gokcumen, J Frasor - International Journal of Molecular …, 2022 - mdpi.com
One of the classic hallmarks of cancer is the imbalance between elevated cell proliferation
and reduced cell death. Ceramide, a bioactive sphingolipid that can regulate this balance …

Global profiling of metabolic adaptation to hypoxic stress in human glioblastoma cells

P Kucharzewska, HC Christianson, M Belting - PloS one, 2015 - journals.plos.org
Oncogenetic events and unique phenomena of the tumor microenvironment together induce
adaptive metabolic responses that may offer new diagnostic tools and therapeutic targets of …