[HTML][HTML] Cell membrane modulation as adjuvant in cancer therapy
S Zalba, TLM Ten Hagen - Cancer treatment reviews, 2017 - Elsevier
Cancer is a complex disease involving numerous biological processes, which can exist in
parallel, can be complementary, or are engaged when needed and as such can replace …
parallel, can be complementary, or are engaged when needed and as such can replace …
Molecular mechanisms of drug resistance and its reversal in cancer
M Kartal-Yandim, A Adan-Gokbulut… - Critical reviews in …, 2016 - Taylor & Francis
Chemotherapy is the main strategy for the treatment of cancer. However, the main problem
limiting the success of chemotherapy is the development of multidrug resistance. The …
limiting the success of chemotherapy is the development of multidrug resistance. The …
New insights into targeting membrane lipids for cancer therapy
G Preta - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Modulation of membrane lipid composition and organization is currently developing as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …
effective therapeutic strategy against a wide range of diseases, including cancer. This field …
Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles
C Peetla, S Vijayaraghavalu, V Labhasetwar - Advanced drug delivery …, 2013 - Elsevier
In this review, we focus on the biophysics of cell membrane lipids, particularly when cancers
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …
Lipidomic landscape in cancer: Actionable insights for membrane‐based therapy and diagnoses
Cancer cells display altered cellular lipid metabolism, including disruption in endogenous
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …
Perturbing the dynamics and organization of cell membrane components: a new paradigm for cancer-targeted therapies
N Bernardes, A M. Fialho - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multi-process disease where different mechanisms exist in parallel to ensure
cell survival and constant adaptation to the extracellular environment. To adapt rapidly …
cell survival and constant adaptation to the extracellular environment. To adapt rapidly …
A comprehensive review on natural occurrence, synthesis and biological activities of glycolipids
Glycolipids are ubiquitous and biologically important molecules and are involved in diverse
biological functions and exhibit biosurfactant applications due to their surface-active and …
biological functions and exhibit biosurfactant applications due to their surface-active and …
Ceramides and their roles in programmed cell death
MB Pilátová, Z Solárová, R Mezencev… - Advances in Medical …, 2023 - Elsevier
Programmed cell death plays a crucial role in maintaining the homeostasis and integrity of
multicellular organisms, and its dysregulation contributes to the pathogenesis of many …
multicellular organisms, and its dysregulation contributes to the pathogenesis of many …
Emerging roles of ceramides in breast cancer biology and therapy
P Pal, GE Atilla-Gokcumen, J Frasor - International Journal of Molecular …, 2022 - mdpi.com
One of the classic hallmarks of cancer is the imbalance between elevated cell proliferation
and reduced cell death. Ceramide, a bioactive sphingolipid that can regulate this balance …
and reduced cell death. Ceramide, a bioactive sphingolipid that can regulate this balance …
Global profiling of metabolic adaptation to hypoxic stress in human glioblastoma cells
P Kucharzewska, HC Christianson, M Belting - PloS one, 2015 - journals.plos.org
Oncogenetic events and unique phenomena of the tumor microenvironment together induce
adaptive metabolic responses that may offer new diagnostic tools and therapeutic targets of …
adaptive metabolic responses that may offer new diagnostic tools and therapeutic targets of …