Recent advances in the molecular pathophysiology of atrial fibrillation
Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
Atrial fibrillation from the pathologist's perspective
D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
Prevention of recurrent lone atrial fibrillation by the angiotensin-II converting enzyme inhibitor ramipril in normotensive patients
F Belluzzi, L Sernesi, P Preti, F Salinaro… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of the present study was to verify whether angiotensin-II converting
enzyme (ACE) inhibition is also effective in preventing relapses of lone atrial fibrillation …
enzyme (ACE) inhibition is also effective in preventing relapses of lone atrial fibrillation …
Monogenic atrial fibrillation as pathophysiological paradigms
Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major
burden, both to patients and to health-care systems. In recent years, increasing evidence …
burden, both to patients and to health-care systems. In recent years, increasing evidence …
Genes and atrial fibrillation: a new look at an old problem
D Fatkin, R Otway, JI Vandenberg - Circulation, 2007 - Am Heart Assoc
tial (Figure 1) and may be less reliant on currents involved in the late phases of
repolarization. 10 A number of ion channels that have a modest effect or that are closed …
repolarization. 10 A number of ion channels that have a modest effect or that are closed …
Genetics of atrial fibrillation: implications for future research directions and personalized medicine
Atrial fibrillation (AF) was first described in humans approximately 100 years ago, 1 and
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
Lone atrial fibrillation: what do we know?
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice.
Despite the common association of AF with cardiovascular disease, some patients can be …
Despite the common association of AF with cardiovascular disease, some patients can be …
Genetics of atrial fibrillation
SA Lubitz, BA Yi, PT Ellinor - Cardiology clinics, 2009 - Elsevier
Recent studies of AF have identified mutations in a series of ion channels; however, these
mutations appear to be relatively rare causes of AF. A genome-wide association study has …
mutations appear to be relatively rare causes of AF. A genome-wide association study has …
Association between angiotensin-converting enzyme insertion/deletion gene polymorphism and atrial fibrillation: a meta-analysis
T Liu, P Korantzopoulos, G Xu, M Shehata, D Li… - Europace, 2011 - academic.oup.com
Aims Recent observations have raised concerns regarding the activation of the renin–
angiotensin system and the development of atrial fibrillation (AF). Some initial studies …
angiotensin system and the development of atrial fibrillation (AF). Some initial studies …
A genetic contribution to risk for postoperative junctional ectopic tachycardia in children undergoing surgery for congenital heart disease
KY Borgman, AH Smith, JP Owen, FA Fish… - Heart rhythm, 2011 - Elsevier
BACKGROUND: Junctional ectopic tachycardia (JET) is a common arrhythmia complicating
pediatric cardiac surgery, with many identifiable clinical risk factors but no genetic risk …
pediatric cardiac surgery, with many identifiable clinical risk factors but no genetic risk …