Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects
the lining of the synovial joints and is associated with progressive disability, premature …

Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

Objectives Since the 2007 recommendations for the management of early arthritis have
been presented, considerable research has been published in the field of early arthritis …

Objectives (1) To investigate the demographic and clinical characteristics contributing to the
delay from symptom onset to the first visit to a rheumatologist;(2) to compare clinical …

Background During the transition to rheumatoid arthritis (RA) many patients pass through a
phase characterised by the presence of symptoms without clinically apparent synovitis …

Background We aimed to investigate the effects of ambient respiratory viral infections in the
general population on rheumatoid arthritis (RA) development. Methods Data of weekly …

The concept of a 'window of opportunity'in treating a disease assumes the existence of a
time frame during which the trajectory of the disease can be effectively and permanently …

Objective Initiation of DMARD-therapy in the 'window of opportunity'is thought to result in a
more effective modification of the processes underlying rheumatoid arthritis (RA). We …

The therapeutic window of opportunity in rheumatoid arthritis (RA) is often referred to.
However, some have questioned whether such a period, in which the disease is more …

Objectives To monitor progression to inflammatory arthritis (IA) in individuals with non-
specific musculoskeletal (MSK) symptoms and positive anticyclic citrullinated peptide (anti …