Regulation by transcription factors in bacteria: beyond description
E Balleza, LN Lopez-Bojorquez… - FEMS microbiology …, 2008 - academic.oup.com
Transcription is an essential step in gene expression and its understanding has been one of
the major interests in molecular and cellular biology. By precisely tuning gene expression …
the major interests in molecular and cellular biology. By precisely tuning gene expression …
Gene silencing H-NS paralogue StpA forms a rigid protein filament along DNA that blocks DNA accessibility
Nucleoid-associated proteins are bacterial proteins that are responsible for chromosomal
DNA compaction and global gene regulation. One such protein is Escherichia coli Histone …
DNA compaction and global gene regulation. One such protein is Escherichia coli Histone …
[HTML][HTML] Structural interplay between DNA-shape protein recognition and supercoiling: the case of IHF
The integration host factor (IHF) is a prominent example of indirect readout as it imposes one
of the strongest bends on relaxed linear DNA. However, the relation between IHF and …
of the strongest bends on relaxed linear DNA. However, the relation between IHF and …
Specific association of teratogen and toxicant metals in hair of newborns with congenital birth defects or developmentally premature birth in a cohort of couples with …
P Manduca, A Naim, S Signoriello - International journal of environmental …, 2014 - mdpi.com
This study was undertaken in Gaza, Palestine, in a cohort of babies born in 2011. Hair
samples of newborns were analyzed for metal load by DRC-ICP-MS. We report specific level …
samples of newborns were analyzed for metal load by DRC-ICP-MS. We report specific level …
Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF)
The integration host factor (IHF) is an abundant nucleoid-associated protein and an
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
Hospital centered surveillance of births in Gaza, Palestine, 2011–2017 and heavy metal contamination of the mothers reveals long-term impact of wars
P Manduca, N Al Baraquni, L Al Baraquni… - Reproductive …, 2019 - Elsevier
Prevalence of preterm, low birth weight and birth defects increased significantly since 2011
in Gaza, Palestine. No change in known co-factors of reproductive health justified this rise …
in Gaza, Palestine. No change in known co-factors of reproductive health justified this rise …
The nucleoid-associated protein Dan organizes chromosomal DNA through rigid nucleoprotein filament formation in E. coli during anoxia
CJ Lim, SY Lee, J Teramoto, A Ishihama… - Nucleic acids …, 2013 - academic.oup.com
Dan is a transcription factor that regulates the ttd operon encoding tartrate dehydratase.
During anaerobic conditions, its copy number increases by 100-fold, making Dan an …
During anaerobic conditions, its copy number increases by 100-fold, making Dan an …
Mechanosensing of DNA bending in a single specific protein-DNA complex
Many crucial biological processes are regulated by mechanical stimuli. Here, we report new
findings that pico-Newton forces can drastically affect the stability of the site-specific DNA …
findings that pico-Newton forces can drastically affect the stability of the site-specific DNA …
Molecular origin of DNA kinking by transcription factors
RK Singh, WD Sasikala… - The Journal of Physical …, 2015 - ACS Publications
Binding of transcription factor (TF) proteins with DNA may cause severe kinks in the latter.
Here, we investigate the molecular origin of the DNA kinks observed in the TF-DNA …
Here, we investigate the molecular origin of the DNA kinks observed in the TF-DNA …
Vital insights into prokaryotic genome compaction by nucleoid-associated protein (NAP) and illustration of DNA flexure angles at single-molecule resolution
Abstract Integration Host Factor (IHF) is a heterodimeric site-specific nucleoid-associated
protein (NAP), well known for its DNA bending ability. Although the IHF induced bending …
protein (NAP), well known for its DNA bending ability. Although the IHF induced bending …