Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …
Clinical trials with mesenchymal stem cells: an update
T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
Immunobiology of mesenchymal stem cells
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …
expanded in vitro. Although their true in situ properties and biological functions remain to be …
Interactions between mesenchymal stem cells and the immune system
N Li, J Hua - Cellular and Molecular Life Sciences, 2017 - Springer
In addition to being multi-potent, mesenchymal stem cells (MSCs) possess
immunomodulatory functions that have been investigated as potential treatments in various …
immunomodulatory functions that have been investigated as potential treatments in various …
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives
Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
Mesenchymal stem cells secrete immunologically active exosomes
Mesenchymal stem cells (MSCs) have been shown to secrete exosomes that are
cardioprotective. Here, we demonstrated that MSC exosome, a secreted membrane vesicle …
cardioprotective. Here, we demonstrated that MSC exosome, a secreted membrane vesicle …
Effects of mesenchymal stem cell-derived exosomes on experimental autoimmune uveitis
L Bai, H Shao, H Wang, Z Zhang, C Su, L Dong, B Yu… - Scientific reports, 2017 - nature.com
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …
Mechanisms of mesenchymal stromal cell immunomodulation
K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …
Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells
P Mattar, K Bieback - Frontiers in immunology, 2015 - frontiersin.org
Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative
medicine, tissue engineering, and immunotherapy. This is based on their differentiation …
medicine, tissue engineering, and immunotherapy. This is based on their differentiation …
[HTML][HTML] Mesenchymal stromal cell exosome–enhanced regulatory T-cell production through an antigen-presenting cell–mediated pathway
Background aims The immunomodulatory property of mesenchymal stromal cell (MSC)
exosomes is well documented. On the basis of our previous report that MSC exosomes …
exosomes is well documented. On the basis of our previous report that MSC exosomes …