Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives

H Yanai, H Yoshida - International journal of molecular sciences, 2019 - mdpi.com
Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Effects of newer antidiabetic drugs on endothelial function and arterial stiffness: a systematic review and meta‐analysis

K Batzias, AS Antonopoulos… - Journal of Diabetes …, 2018 - Wiley Online Library
Background. Newer antidiabetic drugs, ie, dipeptidyl peptidase‐4 (DPP‐4) inhibitors,
sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors, and glucagon‐like peptide‐1 receptor …

Diabetes and calcification: the potential role of anti-diabetic drugs on vascular calcification regression

S Ghosh, D Luo, W He, J Chen, X Su… - Pharmacological Research, 2020 - Elsevier
Vascular calcification (VC) has been well-established as an independent and strong
predictor of cardiovascular diseases (CVD) as well as major cardiac adverse events …

Systematic review and meta-analysis of head-to-head trials comparing sulfonylureas and low hypoglycaemic risk antidiabetic drugs

V Volke, U Katus, A Johannson, K Toompere… - BMC Endocrine …, 2022 - Springer
Background Safety of sulfonylurea drugs in the treatment of Type 2 Diabetes is still under
debate. The aim of this study was to compare the all-cause mortality and cardiovascular …

Diabetes pathogenesis and management: the endothelium comes of age

KM Love, EJ Barrett, SK Malin… - Journal of molecular …, 2021 - academic.oup.com
Endothelium, acting as a barrier, protects tissues against factors that provoke insulin
resistance and type 2 diabetes and itself responds to the insult of insulin resistance inducers …

Effects of dipeptidyl peptidase 4 inhibition on the endothelial control of the vascular tone

JC Ribeiro-Silva, VB Marques… - American Journal of …, 2023 - journals.physiology.org
Dipeptidyl peptidase 4 (DPP4) is a serine protease known to cleave incretin hormones,
which stimulate insulin secretion after food intake, a fact that supported the development of …

Effects of dipeptidyl peptidase-4 inhibitors on renal outcomes in patients with type 2 diabetes: a systematic review and meta-analysis

JH Bae, S Kim, EG Park, SG Kim… - Endocrinology and …, 2019 - synapse.koreamed.org
Background To investigate the effects of dipeptidyl peptidase-4 (DPP-4) inhibitors on renal
outcomes in patients with type 2 diabetes. Methods MEDLINE, Embase, and the Cochrane …

Prediction of treatment outcome in clinical trials under a personalized medicine perspective

P Berchialla, C Lanera, V Sciannameo, D Gregori… - Scientific Reports, 2022 - nature.com
A central problem in most data-driven personalized medicine scenarios is the estimation of
heterogeneous treatment effects to stratify individuals into subpopulations that differ in their …

Effects of antidiabetic drugs on endothelial function in patients with type 2 diabetes mellitus: a Bayesian network meta-analysis

Y Wang, M Yao, J Wang, H Liu, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The changes of endothelial function in type 2 diabetes mellitus (T2DM) patients
are closely associated with the development of cardiovascular disease (CVD). However, it is …

[HTML][HTML] A Comprehensive Review of Clinical Studies Applying Flow-Mediated Dilation

Y Ahn, N Aung, HS Ahn - Diagnostics, 2024 - mdpi.com
Flow-mediated dilation (FMD) is a noninvasive method to evaluate vascular endothelial
function, which manifests the vascular inflammatory response, cell proliferation, and …