The primary bile acids (BAs) are synthetized from cholesterol in the liver, conjugated to
glycine or taurine to increase their solubility, secreted into bile, concentrated in the …

Gallstones grow inside the gallbladder or biliary tract. These stones can be asymptomatic or
symptomatic; only gallstones with symptoms or complications are defined as gallstone …

Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …

Gallstones or cholelithiasis are a major public health problem in Europe and other
developed countries and affect up to 20% of the population. Gallstone disease is the most …

Acute calculus cholecystitis is a very common disease with several area of uncertainty. The
World Society of Emergency Surgery developed extensive guidelines in order to cover grey …

Atherosclerosis is characterized by lipid accumulation, inflammatory response, cell death
and fibrosis in the arterial wall, and is a major pathological basis for ischemic coronary heart …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

An update on the pathogenesis of cholesterol gallstone disea... : Current Opinion in
Gastroenterology An update on the pathogenesis of cholesterol gallstone disease : Current …

Since its publication in 2007, the Tokyo Guidelines for the management of acute cholangitis
and cholecystitis (TG07) have been widely adopted. The validation of TG07 conducted in …

The incidence of gallstone disease has increased in recent years. The pathogenesis of
cholelithiasis is not fully understood. The occurrence of the disease is influenced by both …