Lactate has long been considered a “waste” by-product of cell metabolism, and it
accumulates at sites of inflammation. Recent findings have identified lactate as an active …

Glucose homeostasis is a fundamental aspect of life and its dysregulation is associated with
important diseases, such as cancer and diabetes. Traditionally, glucose radioisotopes have …

This study examined the hypothesis that vitamin-D prevents oxidative stress and
upregulates glucose metabolism via activating insulin-independent signaling molecules in …

Early detection and easy continuous monitoring of emerging or re-emerging infectious,
contagious or other diseases are of particular interest for controlling healthcare advances …

Proximal tubules in the kidney play a crucial role in reabsorbing and eliminating substrates
from the body into the urine, leading to high local concentrations of xenobiotics. This makes …

A scientific explanation for the beneficial role of vitamin D supplementation in the lowering of
glycemia in diabetes remains to be determined. This study examined the biochemical …

Microphysiological systems are an emerging area of in vitro drug development, and their
independent evaluation is important for wide adoption and use. The primary goal of this …

As part of an ongoing search for new antidiabetic agents from medicinal plants, three new
(2, 4, and 5) and two known selaginellin derivatives (1 and 3) were isolated from a methanol …

Irisin, a novel myokine, is secreted by the muscle following proteolytic cleavage of
fibronectin type III domain containing 5 (FNDC5) and is considered a novel regulator of …

Diabetic patients have lower blood concentrations of hydrogen sulfide (H2S), L-cysteine
(LC), and glutathione (GSH). Using C2C12 mouse myotubes as a model, this study …