Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

[HTML][HTML] Integrating the neurodevelopmental and dopamine hypotheses of schizophrenia and the role of cortical excitation-inhibition balance

OD Howes, E Shatalina - Biological psychiatry, 2022 - Elsevier
The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Dendritic cortical microcircuits approximate the backpropagation algorithm

J Sacramento, R Ponte Costa… - Advances in neural …, 2018 - proceedings.neurips.cc
Deep learning has seen remarkable developments over the last years, many of them
inspired by neuroscience. However, the main learning mechanism behind these advances …

[HTML][HTML] Activity-dependent gating of parvalbumin interneuron function by the perineuronal net protein brevican

E Favuzzi, A Marques-Smith, R Deogracias… - Neuron, 2017 - cell.com
Activity-dependent neuronal plasticity is a fundamental mechanism through which the
nervous system adapts to sensory experience. Several lines of evidence suggest that …

[HTML][HTML] Prediction and memory: A predictive coding account

HC Barron, R Auksztulewicz, K Friston - Progress in neurobiology, 2020 - Elsevier
The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …

Inhibitory stabilization and cortical computation

S Sadeh, C Clopath - Nature Reviews Neuroscience, 2021 - nature.com
Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …

[HTML][HTML] Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer's disease

JC Lauterborn, P Scaduto, CD Cox… - Nature …, 2021 - nature.com
Synaptic disturbances in excitatory to inhibitory (E/I) balance in forebrain circuits are thought
to contribute to the progression of Alzheimer's disease (AD) and dementia, although direct …

[HTML][HTML] Disinhibition, a circuit mechanism for associative learning and memory

JJ Letzkus, SBE Wolff, A Lüthi - Neuron, 2015 - cell.com
Although a wealth of data have elucidated the structure and physiology of neuronal circuits,
we still only have a very limited understanding of how behavioral learning is implemented at …

[HTML][HTML] New insights into the pivotal role of the amygdala in inflammation-related depression and anxiety disorder

P Hu, Y Lu, BX Pan, WH Zhang - International Journal of Molecular …, 2022 - mdpi.com
Depression and anxiety disorders are the two most prevalent psychiatric diseases that affect
hundreds of millions of individuals worldwide. Understanding the etiology and related …

Control of synaptic plasticity in deep cortical networks

PR Roelfsema, A Holtmaat - Nature Reviews Neuroscience, 2018 - nature.com
Humans and many other animals have an enormous capacity to learn about sensory stimuli
and to master new skills. However, many of the mechanisms that enable us to learn remain …