Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers
dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has …

BACKGROUND Local control in patients with adenoid cystic carcinoma (ACC) of the head
and neck remains a challenge because of the relative radioresistance of these tumors. This …

Salivary gland cancers (SGCs) are rare, accounting for less than 5% of all malignancies of
the head and neck region, and are morphologically heterogeneous. The diagnosis is mainly …

Purpose Locoregional control (LC) in malignant salivary gland tumors is dose-dependent,
initial results with particle therapy were promising. We report our experience with raster …

In this review, we attempt to make a case for the establishment of a limited number of heavy
ion cancer research and treatment facilities in the United States. Based on the basic physics …

With an incidence of 3–4.5 cases per million, adenoid cystic carcinoma (ACC) of the head
and neck is one of the most common tumors of the parotid and sublingual salivary glands. In …

Purpose To investigate the effect of intensity modulated radiation therapy (IMRT) and dose-
escalated carbon ion (C12) therapy in adenoid cystic carcinoma (ACC) and other malignant …

Abstract Background and Purpose In this multicentric in silico trial we compared photon,
proton, and carbon-ion radiotherapy plans for re-irradiation of patients with squamous cell …