Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Depression is a chronic, recurring, and serious mood disorder that afflicts up to 20% of the
global population. The monoamine hypothesis has dominated our understanding of the …

Adenosine receptor subtypes, first described 40 years ago, are known to regulate diverse
biological functions and have a role in various conditions, such as cerebral and cardiac …

Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

Recent studies combining pharmacological, behavioral, electrophysiological and molecular
approaches indicate that depression results from maladaptive neuroplastic processes …

Astrocytes are fundamental building blocks of the central nervous system. Their dysfunction
has been implicated in many psychiatric disorders, including alcohol use disorder, yet our …

Although posttraumatic stress disorder (PTSD) is on the rise, traumatic events and their
consequences are often hidden or minimized by patients for reasons linked to PTSD itself …

Introduction Depression and anxiety are highly comorbid mental disorders with marked sex
differences. Both disorders show altered activity in the amygdala, hippocampus, and …

Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …