Alzheimer, Parkinson, dementia, and phytochemicals: Insight review

B Can, N Sanlier - Critical reviews in food science and nutrition, 2023 - Taylor & Francis
Abstract Alzheimer's, Parkinson's, and dementia are the leading neurodegenerative
diseases that threaten the world with the aging population. Although the pathophysiology of …

Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease

X Zhou, M Venigalla, R Raju, G Münch - Journal of Neural Transmission, 2022 - Springer
Abstract Prof. Dr. Peter Riederer, the former Head of the Neurochemistry Department of the
Psychiatry and Psychotherapy Clinic at the University of Würzburg (Germany), has been one …

Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum

R Gamage, I Rossetti, G Niedermayer, G Münch… - Journal of …, 2023 - Springer
Background Low-grade, chronic inflammation in the central nervous system characterized
by glial reactivity is one of the major hallmarks for aging-related neurodegenerative …

[HTML][HTML] Curcumin protects PC12 cells from a high glucose-induced inflammatory response by regulating the miR-218-5p/TLR4 axis

Y Cui, HT Song, P Zhang, X Yin, Y Wang, X Wei, XJ Jia - Medicine, 2022 - journals.lww.com
Background: Curcumin exerts a protective effect on diabetic encephalopathy (DN), It is
known for its potent neuroprotective, anti-inflammatory, antioxidant, and anticancer …

Neuroprotective and anti‐inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies

E Azzini, SI Peña‐Corona… - Phytotherapy …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of amyloid‐beta plaques and neurofibrillary tangles, leading to neuronal loss …

A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial …

S Dabrowska, E Turano, I Scambi, F Virla… - International Journal of …, 2024 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive degeneration of upper and lower motor neurons (MNs) in the brain and …

Administration of adipose-derived stem cells extracellular vesicles in a murine model of spinal muscular atrophy: effects of a new potential therapeutic strategy

F Virla, E Turano, I Scambi, L Schiaffino… - Stem cell research & …, 2024 - Springer
Abstract Background Spinal Muscular Atrophy (SMA) is an autosomal-recessive
neuromuscular disease affecting children. It is caused by the mutation or deletion of the …

[HTML][HTML] A Review on Current Aspects of Curcumin-Based Effects in Relation to Neurodegenerative, Neuroinflammatory and Cerebrovascular Diseases

CA Moldoveanu, M Tomoaia-Cotisel… - Molecules, 2024 - mdpi.com
Curcumin is among the most well-studied natural substances, known for its biological
actions within the central nervous system, its antioxidant and anti-inflammatory properties …

Bioactive chemicals in Helianthus tuberosus L may reduce beta-amyloid cytotoxicity as a potential novel treatment for Alzheimer's disease

W Zhu, P Cadet, LS Neuwirth - Studies in natural products chemistry, 2023 - Elsevier
Globally, millions of people are afflicted with Alzheimer's disease (AD), a chronic
neurodegenerative disorder resulting in memory loss and mental dysfunction. The …

A novel solvent-free co-grinding preparation improves curcumin bioavailability in healthy volunteers: A single-center crossover study

C Wang, X Jiang, X Zhang, Y Xu, L Li, X Li, S Wang… - Heliyon, 2023 - cell.com
Curcumin, from the rhizome of turmeric (Curcuma longa L.), has a wide variety of biological
activities. Unfortunately, its poor water-solubility greatly limits its bioavailability. The purpose …