[HTML][HTML] Role of omega-3 fatty acids in cardiovascular disease: the debate continues

SCR Sherratt, P Libby, MJ Budoff, DL Bhatt… - Current atherosclerosis …, 2023 - Springer
Abstract Purpose of Review The omega-3 fatty acids (n3-FAs), eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …

When fat meets the gut—focus on intestinal lipid handling in metabolic health and disease

M Wit, J Trujillo‐Viera, A Strohmeyer… - EMBO Molecular …, 2022 - embopress.org
The regular overconsumption of energy‐dense foods (rich in lipids and sugars) results in
elevated intestinal nutrient absorption and consequently excessive accumulation of lipids in …

Omega-3 and cardiovascular prevention–Is this still a choice?

M Ruscica, CR Sirtori, S Carugo, PC Calder… - Pharmacological …, 2022 - Elsevier
There is currently growing attention being paid to the role of elevated triglycerides (TGs) as
important mediators of residual atherosclerotic cardiovascular disease (ASCVD) risk. This …

Comparative efficacy of omega-3 polyunsaturated fatty acids on major cardiovascular events: A network meta-analysis of randomized controlled trials

B Yang, PT Tseng, X Hu, BY Zeng, JPC Chang… - Progress in Lipid …, 2022 - Elsevier
The role of omega-3 polyunsaturated fatty acids (PUFAs) in primary and secondary
prevention on major cardiovascular events (MCE) is inconclusive due to the potential …

[HTML][HTML] Triglyceride lowering by omega-3 fatty acids: a mechanism mediated by N-acyl taurines

KE Bornfeldt - The Journal of Clinical Investigation, 2021 - Am Soc Clin Investig
Interest in omega-3 fatty acids (colloquially known as fish oils) to lower residual
cardiovascular risk in statin-treated patients has increased markedly in the wake of recent …

[HTML][HTML] Omega-3-fatty acids: do they prevent cardiovascular disease?

RP Mason, SCR Sherratt, RH Eckel - Best Practice & Research Clinical …, 2023 - Elsevier
Despite cardiovascular disease (CVD) reductions with high-intensity statins, there remains
residual risk among patients with metabolic disorders. Alongside low-density lipoproteins …

Function and therapeutic potential of N-acyl amino acids

SA Prakash, RK Kamlekar - Chemistry and physics of lipids, 2021 - Elsevier
N-acyl amino acids (NAAs) are amphiphilic molecules, with different potential fatty acid and
head group moieties. NAAs are the largest family of anandamide congener lipids discovered …

[HTML][HTML] Omega-3 (n-3) Fatty Acid–Statin Interaction: Evidence for a Novel Therapeutic Strategy for Atherosclerotic Cardiovascular Disease

I Djuricic, PC Calder - Nutrients, 2024 - mdpi.com
Managing atherosclerotic cardiovascular disease (ASCVD) often involves a combination of
lifestyle modifications and medications aiming to decrease the risk of cardiovascular …

Fish and Omega-3 Fatty Acids: Sex and Racial Differences in Cardiovascular Outcomes and Cognitive Function

FK Welty, R Daher, M Garelnabi - … , Thrombosis, and Vascular …, 2024 - Am Heart Assoc
Both cardiovascular disease (CVD) and cognitive decline are common features of aging.
One in 5 deaths is cardiac for both men and women in the United States, and an estimated …

Docosahexaenoic acid‐acylated astaxanthin monoester ameliorates chronic high‐fat diet‐induced autophagy dysfunction via ULK1 pathway in the hypothalamus of …

X Wang, P Cong, X Wang, Z Wang… - Journal of the …, 2023 - Wiley Online Library
Background Dietary astaxanthin (AST) exhibits the ability to resist lipid accumulation and
stimulate hepatic autophagy. Natural AST predominantly exists in stable esterified forms …