Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Angiogenesis in pancreatic cancer: current research status and clinical implications
S Li, HX Xu, CT Wu, WQ Wang, W Jin, HL Gao, H Li… - Angiogenesis, 2019 - Springer
Pancreatic cancer is one of the most lethal malignancies worldwide. Although the standard
of care in pancreatic cancer has improved, prognoses for patients remain poor with a 5-year …
of care in pancreatic cancer has improved, prognoses for patients remain poor with a 5-year …
Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning
P Vempati, AS Popel, F Mac Gabhann - Cytokine & growth factor reviews, 2014 - Elsevier
The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …
neovascularization in numerous tissues under physiological and pathological conditions …
Tumor angiogenesis revisited: regulators and clinical implications
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
Endothelial cell plasticity at the single-cell level
A Pasut, LM Becker, A Cuypers, P Carmeliet - Angiogenesis, 2021 - Springer
The vascular endothelium is characterized by a remarkable level of plasticity, which is the
driving force not only of physiological repair/remodeling of adult tissues but also of …
driving force not only of physiological repair/remodeling of adult tissues but also of …
Overview on the different patterns of tumor vascularization
D Ribatti, F Pezzella - Cells, 2021 - mdpi.com
Angiogenesis is a crucial event in the physiological processes of embryogenesis and wound
healing. During malignant transformation, dysregulation of angiogenesis leads to the …
healing. During malignant transformation, dysregulation of angiogenesis leads to the …
Intussusceptive angiogenesis: a biologically relevant form of angiogenesis
W De Spiegelaere, C Casteleyn… - Journal of vascular …, 2012 - karger.com
Angiogenesis, ie the development and growth of blood vessels, is a major topic of research
as it plays an important role in normal development and in various pathologies. Recent …
as it plays an important role in normal development and in various pathologies. Recent …
Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
The impact of discontinuation of anti-VEGF cancer therapy in promoting cancer metastasis is
unknown. Here we show discontinuation of anti-VEGF treatment creates a time-window of …
unknown. Here we show discontinuation of anti-VEGF treatment creates a time-window of …
Intussusceptive microvascular growth in tumors
D Ribatti, V Djonov - Cancer letters, 2012 - Elsevier
Intussusception is an alternative to the sprouting mode of angiogenesis. The advantage of
this mechanism of vascular growth is that blood vessels are generated more rapidly and the …
this mechanism of vascular growth is that blood vessels are generated more rapidly and the …
Combination antiangiogenic therapy and radiation in head and neck cancers
Tumor angiogenesis is a hallmark of advanced cancers and promotes invasion and
metastasis. Over 90% of head and neck squamous cell carcinomas (HNSCC) express …
metastasis. Over 90% of head and neck squamous cell carcinomas (HNSCC) express …