In the past, conventional drug discovery strategies have been successfully employed to
develop new drugs, but the process from lead identification to clinical trials takes more than …

Global emergence of Tigecycline resistant Acinetobacter baumannii (TRAB) is on the
horizon and poses a very serious threat to human health. There is a pressing demand for …

Extraction technology can influence the vegetable oil functional quality. Polyphenols in
rapeseed oil have been proved to be beneficial for cardiovascular health. In this study, we …

The Cytochrome P450 family of heme-containing proteins plays a major role in catalyzing
phase I metabolic reactions, and the CYP3A4 subtype is responsible for the metabolism of …

Abstract Kallikrein-8, a serine protease, is a target for structure-based drug design due to its
therapeutic potential in treating Alzheimer's disease and is also useful as a biomarker in …

Aurora kinase B plays an important role in the cell cycle to orchestrate the mitotic process.
The amplification and overexpression of this kinase have been implicated in several human …

The study aimed to screen prospective molecular targets of BCC and potential natural lead
candidates as effective binders by computational modeling, molecular docking, and dynamic …

Francisella tularensis is a Gram-negative bacterium and is the etiological agent of taluremia.
The prolonged use of antibiotics is the reason for pathogen resistance to antibiotics such as …

Acinetobacter baumannii belongs to the most critical group of bacterial pathogens that are
resistant to large number of antibiotics, including the highly effective carbapenems and third …

The rapidity and high-throughput nature of in silico technologies make them advantageous
for predicting the properties of a large array of substances. In silico approaches can be used …