Based on the principles and metrics of green chemistry and sustainable development,
biocatalysis is both a green and sustainable technology. This is largely a result of the …

Continuous manufacturing and Green Chemistry, are two promising approaches to
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …

The continuous flow synthesis of active pharmaceutical ingredients, value-added chemicals,
and materials has grown tremendously over the past ten years. This revolution in chemical …

Catalytic enantioselective transformations provide well-established and direct access to
stereogenic synthons that are broadly distributed among active pharmaceutical ingredients …

Biocatalysis has widened its scope and relevance since new molecular tools, including
improved expression systems for proteins, protein and metabolic engineering, and rational …

Biocatalysts represent an efficient, highly selective and greener alternative to metal catalysts
in both industry and academia. In the last two decades, the interest in biocatalytic …

Highlights•Process intensification through upstream and downstream processing is an
important tool to increase the overall productivity of continuous biocatalysis.•Immobilization …

The continuous flow synthesis of a series of amines was successfully achieved by exploiting
the enhanced stability and broad substrate scope of an immobilised transaminase from …

Biocatalysis offers an alternative approach to conventional chemical processes for the
production of single-isomer chiral drugs. Lipases are one of the most used enzymes in the …

Recent advances in the field of continuous flow chemistry allow the multistep preparation of
complex molecules such as APIs (Active Pharmaceutical Ingredients) in a telescoped …