Mitochondrial glucocorticoid receptors and their actions

I Kokkinopoulou, P Moutsatsou - International journal of molecular …, 2021 - mdpi.com
Mitochondria are membrane organelles present in almost all eukaryotic cells. In addition to
their well-known role in energy production, mitochondria regulate central cellular processes …

Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion

M Christophe, S Nicolas - Current pharmaceutical design, 2006 - ingentaconnect.com
Evidence obtained over the past two decades shows that reactive oxygen species (ROS) are
involved in brain lesions, including those due to cerebral ischemia-reperfusion. The …

Pharmacology of acute mountain sickness: old drugs and newer thinking

ER Swenson - Journal of Applied Physiology, 2016 - journals.physiology.org
Pharmacotherapy in acute mountain sickness (AMS) for the past half century has largely
rested on the use of carbonic anhydrase (CA) inhibitors, such as acetazolamide, and …

Glucocorticoids, metabolism and brain activity

A Jaszczyk, GR Juszczak - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The review integrates different experimental approaches including biochemistry, c-Fos
expression, microdialysis (glutamate, GABA, noradrenaline and serotonin) …

Glucocorticoids and their receptors: insights into specific roles in mitochondria

SR Lee, HK Kim, IS Song, J Youm, LA Dizon… - Progress in biophysics …, 2013 - Elsevier
Glucocorticoids (GCs) affect most physiological systems and are the most frequently used
drugs for multiple disorders and organ transplantation. GC functions depend on a balance …

Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction

DA Tata, BK Yamamoto - Addiction, 2007 - Wiley Online Library
Aims Methamphetamine is an amphetamine derivative that is abused increasingly world‐
wide at an alarming rate over the last decade. Pre‐clinical and human studies have shown …

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

MS Breen, LM Bierer, NP Daskalakis, HN Bader… - Translational …, 2019 - nature.com
Post-traumatic stress disorder (PTSD) is a condition of stress reactivity, whose clinical
manifestations are evident when patients are triggered following exposure to a traumatic …

Non-genomic effect of glucocorticoids on cardiovascular system

SR Lee, HK Kim, JB Youm, LA Dizon, IS Song… - … -European Journal of …, 2012 - Springer
Glucocorticoids (GCs) are essential steroid hormones for homeostasis, development,
metabolism, and cognition and possess anti-inflammatory and immunosuppressive actions …

[HTML][HTML] Environmental and behavioral regulation of HIF-mitochondria crosstalk

J Burtscher, E Hohenauer, M Burtscher… - Free Radical Biology …, 2023 - Elsevier
Reduced oxygen availability (hypoxia) can lead to cell and organ damage. Therefore,
aerobic species depend on efficient mechanisms to counteract detrimental consequences of …

Metabolic profiling reveals therapeutic biomarkers of processed Aconitum Carmichaeli Debx in treating hydrocortisone induced Kidney-Yang deficiency syndrome rats

Y Tan, X Liu, C Lu, X He, J Li, C Xiao, M Jiang… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Kidney-Yang Deficiency syndrome (KYDS) is a
diagnostic pattern in traditional Chinese medicine (TCM) and clinical data showed that the …