Peptide‐based diagnostic and therapeutic agents: Where we are and where we are heading?
MP Khalily, M Soydan - Chemical Biology & Drug Design, 2023 - Wiley Online Library
Peptides are increasingly present in all branches of medicine as innovative drugs, imaging
agents, theragnostic, and constituent moieties of other sophisticated drugs such as peptide …
agents, theragnostic, and constituent moieties of other sophisticated drugs such as peptide …
Polymeric nanoparticles as a promising platform for treating triple-negative breast cancer: Current status and future perspectives
MA Bazzazan, P Fathollazadeh, SK Shahbaz… - International Journal of …, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that
lacks expression of estrogen, progesterone, and HER2 receptor targets for therapy …
lacks expression of estrogen, progesterone, and HER2 receptor targets for therapy …
A Magnetic Resonance Imaging‐Chemical Exchange Saturation Transfer (MRI‐CEST) Method for the Detection of Water Cycling across Cellular Membranes
E Di Gregorio, C Papi, L Conti, A Di Lorenzo… - Angewandte …, 2024 - Wiley Online Library
Water cycling across the membrane transporters is considered a hallmark of cellular
metabolism and it could be of high diagnostic relevance in the characterization of tumors …
metabolism and it could be of high diagnostic relevance in the characterization of tumors …
Delivery of RGD-modified liposome as a targeted colorectal carcinoma therapy and its autophagy mechanism
Y Ren, B Yuan, S Hou, Y Sui, T Yang, M Lv… - Journal of Drug …, 2021 - Taylor & Francis
Liposomes are among the most extensively applied drug carriers due to their excellent
biocompatibility, controllable size and ease of modification. In the present study, we …
biocompatibility, controllable size and ease of modification. In the present study, we …
[HTML][HTML] Evaluation of physicochemical properties, pharmacokinetics, biodistribution, toxicity, and contrast-enhanced cancer MRI of a cancer-targeting contrast agent …
Y Li, S Gao, H Jiang, N Ayat, V Laney… - Investigative …, 2022 - journals.lww.com
Objectives Preclinical assessments were performed according to the US Food and Drug
Administration guidelines to determine the physicochemical properties, pharmacokinetics …
Administration guidelines to determine the physicochemical properties, pharmacokinetics …
RGD_PLGA nanoparticles with docetaxel: a route for improving drug efficiency and reducing toxicity in breast cancer treatment
E Di Gregorio, C Romiti, A Di Lorenzo, F Cavallo… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most prevalent cancer in women and the leading
cause of cancer-associated deaths. Although several therapeutic approaches are available …
cause of cancer-associated deaths. Although several therapeutic approaches are available …
Development of tLyP-1 functionalized nanoliposomes with tunable internal water phase for glioma targeting
Y Wang, Z Ding, S Lv, J Liu, J Pan, Y Yu… - Journal of Liposome …, 2023 - Taylor & Francis
Abstract tLyP-1 peptide is verified to recognize neuropilin (NRP) receptors overexpressed
on the surface of both glioma cells and endothelial cells of angiogenic blood vessels. In the …
on the surface of both glioma cells and endothelial cells of angiogenic blood vessels. In the …
Reliable assessment of swine renal fibrosis using quantitative magnetization transfer imaging
K Jiang, CM Ferguson, RC Grimm, X Zhu… - Investigative …, 2022 - journals.lww.com
Objectives Quantitative magnetization transfer (qMT) is useful for measurement of murine
renal fibrosis at high and ultrahigh field strengths. However, its utility at clinical field …
renal fibrosis at high and ultrahigh field strengths. However, its utility at clinical field …