Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease
Introduction: There is a growing body of evidence to suggest that chronic silent inflammation
is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and …
is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and …
Autophagy in vascular disease
GRY De Meyer, MOJ Grootaert, CF Michiels… - Circulation …, 2015 - Am Heart Assoc
Autophagy is a reparative, life-sustaining process by which cytoplasmic components are
sequestered in double-membrane vesicles and degraded on fusion with lysosomal …
sequestered in double-membrane vesicles and degraded on fusion with lysosomal …
Damage-associated molecular patterns in tumor radiotherapy
Radiotherapy is one of the most common modalities for the treatment of cancer. One of the
most promising effects of radiotherapy is immunologic cell death and the release of danger …
most promising effects of radiotherapy is immunologic cell death and the release of danger …
Metformin: an old drug for the treatment of diabetes but a new drug for the protection of the endothelium
The anti-diabetic and oral hypoglycaemic agent metformin, first used clinically in 1958, is
today the first choice or 'gold standard'drug for the treatment of type 2 diabetes and …
today the first choice or 'gold standard'drug for the treatment of type 2 diabetes and …
mTOR inhibition: a promising strategy for stabilization of atherosclerotic plaques
Statins are currently able to stabilize atherosclerotic plaques by lowering plasma cholesterol
and pleiotropic effects, but a residual risk for atherosclerotic disease remains. Therefore …
and pleiotropic effects, but a residual risk for atherosclerotic disease remains. Therefore …
Roles of TGF-β signaling pathway in tumor microenvirionment and cancer therapy
H Zhao, J Wei, J Sun - International Immunopharmacology, 2020 - Elsevier
Transforming growth factor β (TGF-β) signaling pathway has pleiotropic effects on cell
proliferation, differentiation, adhesion, senescence, and apoptosis. TGF-β can be widely …
proliferation, differentiation, adhesion, senescence, and apoptosis. TGF-β can be widely …
Exosomal microRNA-98-5p from hypoxic bone marrow mesenchymal stem cells inhibits myocardial ischemia–reperfusion injury by reducing TLR4 and activating the …
L Zhang, Q Wei, X Liu, T Zhang, S Wang, L Zhou… - International …, 2021 - Elsevier
Objective MicroRNAs (miRNAs) are essential biomarkers during development of human
diseases. We aimed to explore the role of hypoxia-induced bone marrow mesenchymal …
diseases. We aimed to explore the role of hypoxia-induced bone marrow mesenchymal …
Research advances on circulating long noncoding RNAs as biomarkers of cardiovascular diseases
M Cao, H Luo, D Li, S Wang, L Xuan, L Sun - International Journal of …, 2022 - Elsevier
Cardiovascular diseases (CVD) such as myocardial ischemia, myocardial infarction, heart
failure, atherosclerosis, hypertension, arrhythmia, and their complications diseases are …
failure, atherosclerosis, hypertension, arrhythmia, and their complications diseases are …
Salvianolic acid C improves cerebral ischemia reperfusion injury through suppressing microglial cell M1 polarization and promoting cerebral angiogenesis
H Shen, H Pei, L Zhai, Q Guan, G Wang - International …, 2022 - Elsevier
This study aimed to investigate the mechanism of salvianolic acid C (SAC), the active
ingredient in Salvia miltiorrhiza, in improving cerebral ischemia injury. The mouse microglial …
ingredient in Salvia miltiorrhiza, in improving cerebral ischemia injury. The mouse microglial …
Diet components can suppress inflammation and reduce cancer risk
WE Hardman - Nutrition research and practice, 2014 - synapse.koreamed.org
Epidemiology studies indicate that diet or specific dietary components can reduce the risk for
cancer, cardiovascular disease and diabetes. An underlying cause of these diseases is …
cancer, cardiovascular disease and diabetes. An underlying cause of these diseases is …