Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

Microfluidic impedance cytometry for single-cell sensing: Review on electrode configurations

S Zhu, X Zhang, Z Zhou, Y Han, N Xiang, Z Ni - Talanta, 2021 - Elsevier
Single-cell analysis has gained considerable attention for disease diagnosis, drug
screening, and differentiation monitoring. Compared to the well-established flow cytometry …

Microfluidic impedance‐deformability cytometry for label‐free single neutrophil mechanophenotyping

C Petchakup, H Yang, L Gong, L He, HM Tay, R Dalan… - Small, 2022 - Wiley Online Library
The intrinsic biophysical states of neutrophils are associated with immune dysfunctions in
diseases. While advanced image‐based biophysical flow cytometers can probe cell …

Continuous microfluidic 3D focusing enabling microflow cytometry for single-cell analysis

S Yan, D Yuan - Talanta, 2021 - Elsevier
Single-cell analysis is developed with an aim to understand the cellular heterogeneity,
including protein content, DNA, RNA, as well as the cellular metabolism. Microflow cytometry …

Inertial microfluidics for high-throughput cell analysis and detection: a review

Z Zhou, Y Chen, S Zhu, L Liu, Z Ni, N Xiang - Analyst, 2021 - pubs.rsc.org
Since it was first proposed in 2007, inertial microfluidics has been extensively studied in
terms of theory, design, fabrication, and application. In recent years, with the rapid …

Oscillatory viscoelastic microfluidics for efficient focusing and separation of nanoscale species

M Asghari, X Cao, B Mateescu, D van Leeuwen… - ACS …, 2019 - ACS Publications
The ability to precisely control particle migration within microfluidic systems is essential for
focusing, separating, counting, and detecting a wide range of biological species. To date …

Microfluidic flow cytometry for blood-based biomarker analysis

Y Zhang, Y Zhao, T Cole, J Zheng, J Guo, SY Tang - Analyst, 2022 - pubs.rsc.org
Flow cytometry has proven its capability for rapid and quantitative analysis of individual cells
and the separation of targeted biological samples from others. The emerging microfluidics …

Asymmetric serpentine microchannel based impedance cytometer enabling consistent transit and accurate characterization of tumor cells and blood cells

D Tang, M Chen, Y Han, N Xiang, Z Ni - Sensors and Actuators B …, 2021 - Elsevier
A consistent cell transit position is essential for accurately characterize cellular impedance
signature. In this paper, we integrated asymmetric serpentine structure and elasto-inertial …

Recent advances in deformation-assisted microfluidic cell sorting technologies

J Sun, X Huang, J Chen, R Xiang, X Ke, S Lin, W Xuan… - Analyst, 2023 - pubs.rsc.org
Cell sorting is an essential prerequisite for cell research and has great value in life science
and clinical studies. Among the many microfluidic cell sorting technologies, label-free …

Microfluidic systems for blood and blood cell characterization

H Kim, A Zhbanov, S Yang - Biosensors, 2022 - mdpi.com
A laboratory blood test is vital for assessing a patient's health and disease status. Advances
in microfluidic technology have opened the door for on-chip blood analysis. Currently …