Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …

The human pangenome, a new reference sequence, addresses many limitations of the
current GRCh38 reference. The first release is based on 94 high-quality haploid assemblies …

Contaminations frequently occur in bacterial cultures, which significantly affect the
reproducibility and reliability of the results from whole-genome sequencing (WGS) …

Pangenomes are replacing single reference genomes to capture all variants within a
species or clade, but their analysis predominantly leverages graph-based methods that …

Cancer is a deadly disease with actual cause still being an unknown mystery. Classifying
the different kinds of tumors is rather essential for diagnosing cancer and discovering new …

ABSTRACT The Human Pangenome is a new reference build that addresses many of the
limitations of the current reference. The first release is based on 94 high-quality haploid …

High throughput sequencing technologies generate massive amounts of biological
sequence datasets as costs fall. One of the current algorithmic challenges for exploiting …

K-mer frequency statistics can be used to reveal subsequence distribution patterns in
biological sequences. It is a crucial instrument for measuring sequence similarity and thus …

The rapid progression of genomics and proteomics has been driven by the advent of
advanced sequencing technologies, large, diverse, and readily available omics datasets …