Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

Sleep disturbances and dementia are two common and significant health problems in older
adults. Investigations suggest that sleep disturbances might increase the risk of dementia …

Disruptions of normal circadian rhythms and sleep cycles are consequences of aging and
can profoundly affect health. Accumulating evidence indicates that circadian and sleep …

An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Abstract Study Objectives: Mounting evidence implicates disturbed sleep or lack of sleep as
one of the risk factors for Alzheimer's disease (AD), but the extent of the risk is uncertain. We …

Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing
substantial distress for both people with dementia and their caregivers, and contributing to …

Aging is characterized by changes in the structure and quality of sleep. When the alterations
in sleep become substantial, they can generate or accelerate cognitive decline, even in the …

Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …

Sleep is an essential human function but its regulation is poorly understood. Using
accelerometer data from 85,670 UK Biobank participants, we perform a genome-wide …

Sleep is implicated in cognitive functioning in young adults. With increasing age, there are
substantial changes to sleep quantity and quality, including changes to slow-wave sleep …