Human T-cell receptor variable gene segment families

B Arden, SP Clark, D Kabelitz, TW Mak - Immunogenetics, 1995 - Springer
Multiple DNA and protein sequence alignments have been constructed for the human T-cell
receptor α/δ, β, and γ (TCRA/D, B, and G) variable (V) gene segments. The traditional …

Diagnostic role of tests for T cell receptor (TCR) genes

E Hodges, MT Krishna, C Pickard… - Journal of clinical …, 2003 - jcp.bmj.com
Rapid advances in molecular biological techniques have made it possible to study disease
pathogenesis at a genomic level. T cell receptor (TCR) gene rearrangement is an important …

The extent of the human germline T-cell receptor V beta gene segment repertoire

S Wei, P Charmley, MA Robinson, P Concannon - Immunogenetics, 1994 - Springer
An assessment of the size of the human TCRBV gene segment repertoire based on the
identification of TCRBV gene segments in genomic DNA was undertaken. PCR amplification …

Class I and class II major histocompatibility complex alleles are associated with faecal egg counts following natural, predominantly Ostertagia circumcincta infection

J Buitkamp, P Filmether, MJ Stear, JT Epplen - Parasitology research, 1996 - Springer
During a previous investigation an association was found between major histocompatibility
complex (MHC)-DRB1 alleles and faecal egg counts following natural infection …

Typing of artiodactyl MHC‐DRB genes with the help of intronic simple repeated DNA sequences

FW Schwaiger, J Buitkamp, E Weyers… - Molecular …, 1993 - Wiley Online Library
An efficient oligonucleotide typing method for the highly polymorphic MHC‐DRB genes is
described for artiodactyls like cattle, sheep and goat. By means of the polymerase chain …

SLE nephritis is associated with an oligoclonal expansion of intrarenal T cells

SF Massengill, MM Goodenow, JW Sleasman - American journal of kidney …, 1998 - ajkd.org
Autoimmune systemic lupus erythematosus (SLE) nephritis is characterized by the influx of
mononuclear inflammatory cell infiltrates within the glomeruli and renal interstitium. To …

Selected di-and tetranucleotide microsatellites from chromosomes 7, 12, 14, and Y in various Eurasian populations

M Gomolka, J Hundrieser, P Nürnberg, L Roewer… - Human genetics, 1994 - Springer
Microsatellite polymorphisms of nine Eurasian populations (> 1200 chromosomes) were
analyzed for the following loci: i) intronic (gt) n stretches of three T cell receptor (TCR) B loci …

Non-random employment of Vβ6 and Jβ gene elements and conserved amino acid usage profiles in CDR3 regions of human fetal and adult TCR β chain …

FM Raaphorst, EL Kaijzel, MJD van Tol… - International …, 1994 - academic.oup.com
We have studied the usage of Vβ36, Dβ, and Jβ elements, and the composition of the CDR3
regions of human fetal TCR β chain rearrangements In a 17 week old fetal thymus and In …

[图书][B] The molecular pathology of autoimmune diseases

AN Theofilopoulos, CA Bona - 2002 - taylorfrancis.com
Remarkable advances have been made in the pathogenesis of autoimmunity, such as with
bone marrow transplantation, which is becoming a powerful strategy in treating certain life …

On simple repetitive DNA sequences and complex diseases

C Epplen, EJM Santos, W Mäueler… - …, 1997 - Wiley Online Library
Simple repetitive DNA sequences are abundantly interspersed in eukaryote genomes and
therefore useful in genome research and genetic fingerprinting in plants, fungi and animals …