Natural phytochemicals as novel therapeutic strategies to prevent and treat Parkinson's disease: current knowledge and future perspectives
R Balakrishnan, S Azam, DY Cho… - Oxidative Medicine …, 2021 - Wiley Online Library
Parkinson's disease (PD) is the second‐most common neurodegenerative chronic disease
affecting both cognitive performance and motor functions in aged people. Yet despite the …
affecting both cognitive performance and motor functions in aged people. Yet despite the …
[HTML][HTML] Plant flavonoids on oxidative stress-mediated kidney inflammation
S Alsawaf, F Alnuaimi, S Afzal, RM Thomas… - Biology, 2022 - mdpi.com
Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …
Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating …
In the present study, the protective effects of quercetin on peripheral neurotoxicity caused by
vincristine, which is used effectively in the treatment of various types of cancers, were …
vincristine, which is used effectively in the treatment of various types of cancers, were …
Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress …
SS Ibrahim, OGA Elseoud, MH Mohamedy, MM Amer… - …, 2021 - Elsevier
Many cancer survivors suffer from chemotherapy-induced cognitive impairment known as
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …
Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-κB, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways
Aim Acrylamide (AC) is a carcinogenic substance which is formed during the heating of
starchy foods at high temperatures and constitutes an important risk for human health …
starchy foods at high temperatures and constitutes an important risk for human health …
Chrysin mitigates diclofenac-induced hepatotoxicity by modulating oxidative stress, apoptosis, autophagy and endoplasmic reticulum stress in rats
Background Diclofenac (DF) is a non-steroidal anti-inflammatory drug (NSAID) generally
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
Protective effects of curcumin against paclitaxel-induced spinal cord and sciatic nerve injuries in rats
Paclitaxel (PTX) is an antineoplastic agent commonly used in the treatment of solid tumors
and is known to cause dose-limiting peripheral neurotoxicity. This study was performed to …
and is known to cause dose-limiting peripheral neurotoxicity. This study was performed to …