The convergence of extracellular vesicle and GPCR biology
Transmembrane receptors, of which G protein-coupled receptors (GPCRs) constitute the
largest group, typically act as cellular antennae that reside at the plasma membrane (PM) to …
largest group, typically act as cellular antennae that reside at the plasma membrane (PM) to …
Accessory ESCRT-III proteins selectively regulate Rab11-exosome biogenesis in Drosophila secondary cells
Exosomes are secreted nanovesicles with potent signalling activity that are initially formed
as intraluminal vesicles (ILVs) in multivesicular endosomes, which subsequently fuse with …
as intraluminal vesicles (ILVs) in multivesicular endosomes, which subsequently fuse with …
GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery
Extracellular vesicles (EVs) are biological nanoparticles with important roles in intercellular
communication and pathophysiology. Their capacity to transfer biomolecules between cells …
communication and pathophysiology. Their capacity to transfer biomolecules between cells …
Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals
RB Walsh, AN Becalska, MJ Zunitch, T Lemos… - BioRxiv, 2019 - biorxiv.org
Neuronal extracellular vesicles (EVs) play important roles in intercellular communication
and pathogenic protein propagation in neurological disease. However, it remains unclear …
and pathogenic protein propagation in neurological disease. However, it remains unclear …