siRNA: Mechanism of action, challenges, and therapeutic approaches

W Alshaer, H Zureigat, A Al Karaki, A Al-Kadash… - European journal of …, 2021 - Elsevier
Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

Respiratory syncytial virus infection in adults

HH Nam, MG Ison - bmj, 2019 - bmj.com
Human respiratory syncytial virus (RSV) belongs to the recently defined Pneumoviridae
family, Orthopneumovirus genus. It is a negative sense, single stranded RNA virus that …

Characteristics and outcomes of coronavirus infection in children: the role of viral factors and an immunocompromised state

C Ogimi, JA Englund, MC Bradford, X Qin… - Journal of the …, 2019 - academic.oup.com
Background Immunocompromised children might be predisposed to serious infections from
human coronaviruses (HCoVs), including strains OC43, NL63, HKU1, and 229E; however …

Respiratory syncytial virus

A Jha, H Jarvis, C Fraser… - SARS, MERS and other …, 2016 - library.oapen.org
Respiratory syncytial virus (RSV) infection has an estimated global incidence of 33 million
cases in children younger than 5 years, with 10% requiring hospital admission and up to …

The natural history of influenza infection in the severely immunocompromised vs nonimmunocompromised hosts

MJ Memoli, R Athota, S Reed… - Clinical infectious …, 2014 - academic.oup.com
Introduction. Medical advances have led to an increase in the world's population of
immunosuppressed individuals. The most severely immunocompromised patients are those …

Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus …

HH Hirsch, R Martino, KN Ward… - Clinical infectious …, 2013 - academic.oup.com
Community-acquired respiratory virus (CARV) infections have been recognized as a
significant cause of morbidity and mortality in patients with leukemia and those undergoing …

Clinical and epidemiologic features of respiratory syncytial virus

CB Hall, EAF Simőes, LJ Anderson - Challenges and opportunities for …, 2013 - Springer
Since its discovery in 1955, respiratory syncytial virus (RSV) has consistently been noted to
be the single most important cause of lower respiratory tract illness in infants< 1 year of age …

Going viral—RSV as the neglected adult respiratory virus

B Busack, AF Shorr - Pathogens, 2022 - mdpi.com
Human respiratory syncytial virus (RSV) is increasingly recognized as a significant viral
pathogen in adults with acute respiratory illness, particularly in the elderly, the …

Respiratory viral infections in patients with cancer or undergoing hematopoietic cell transplant

DR Hijano, G Maron, RT Hayden - Frontiers in microbiology, 2018 - frontiersin.org
Survival rates for pediatric cancer have steadily improved over time but it remains a
significant cause of morbidity and mortality among children. Infections are a major …

[HTML][HTML] The “ABC” of virus-specific T cell immunity in solid organ transplantation

M Sester, C Leboeuf, T Schmidt, HH Hirsch - American Journal of …, 2016 - Elsevier
Transplant patients are at increased risk of viral complications due to impaired control of
viral replication, resulting from HLA mismatching between graft and host and the …