Fetal brain development in congenital heart disease

S Peyvandi, C Rollins - Canadian Journal of Cardiology, 2023 - Elsevier
Neurodevelopmental impairments are the most common extracardiac morbidities among
patients with complex congenital heart disease (CHD) across the lifespan. Robust clinical …

Fetal brain volume predicts neurodevelopment in congenital heart disease

A Sadhwani, D Wypij, V Rofeberg, A Gholipour… - Circulation, 2022 - Am Heart Assoc
Background: Neurodevelopmental impairment is common in children with congenital heart
disease (CHD), but postnatal variables explain only 30% of the variance in outcomes. To …

The genetics of neurodevelopment in congenital heart disease

E Patt, A Singhania, AE Roberts, SU Morton - Canadian Journal of …, 2023 - Elsevier
Congenital heart disease (CHD) is the most common birth anomaly, affecting almost 1% of
infants. Neurodevelopmental delay is the most common extracardiac feature in people with …

Normal growth, sexual dimorphism, and lateral asymmetries at fetal brain MRI

F Machado-Rivas, J Gandhi, JJ Choi, C Velasco-Annis… - Radiology, 2022 - pubs.rsna.org
Background Tools in image reconstruction, motion correction, and segmentation have
enabled the accurate volumetric characterization of fetal brain growth at MRI. Purpose To …

[HTML][HTML] Fetal brain tissue annotation and segmentation challenge results

K Payette, HB Li, P de Dumast, R Licandro, H Ji… - Medical image …, 2023 - Elsevier
In-utero fetal MRI is emerging as an important tool in the diagnosis and analysis of the
developing human brain. Automatic segmentation of the developing fetal brain is a vital step …

[HTML][HTML] BOUNTI: Brain vOlumetry and aUtomated parcellatioN for 3D feTal MRI

AU Uus, V Kyriakopoulou, A Makropoulos… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Fetal MRI is widely used for quantitative brain volumetry studies. However, currently, there is
a lack of universally accepted protocols for fetal brain parcellation and segmentation …

[HTML][HTML] Quantification of sulcal emergence timing and its variability in early fetal life: hemispheric asymmetry and sex difference

HJ Yun, HJ Lee, JY Lee, T Tarui, CK Rollins… - NeuroImage, 2022 - Elsevier
Human fetal brains show regionally different temporal patterns of sulcal emergence
following a regular timeline, which may be associated with spatiotemporal patterns of gene …

Magnetic resonance spectroscopy of brain metabolism in fetuses with congenital heart disease

NN Andescavage, S Pradhan, AC Gimovsky… - Journal of the American …, 2023 - jacc.org
Background Congenital heart disease (CHD) remains a significant risk factor for neurologic
injury because altered fetal hemodynamics may be unable to support typical brain …

Neuroimaging and Neurodevelopmental Outcomes Among Individuals With Complex Congenital Heart Disease: JACC State-of-the-Art Review

K Phillips, B Callaghan, V Rajagopalan, F Akram… - Journal of the American …, 2023 - jacc.org
Although neuroimaging advances have deepened our understanding of brain health in
individuals with congenital heart disease (CHD), it is less clear how neuroimaging findings …

Preterm congenital heart disease and neurodevelopment: the importance of looking beyond the initial hospitalization

JA Katz, PT Levy, SC Butler, A Sadhwani… - Journal of …, 2023 - nature.com
Congenital heart disease (CHD) and prematurity are leading causes of infant mortality in the
United States. Infants with CHD born prematurely are often described as facing “double …