Disease manifestations and pathogenic mechanisms of group A Streptococcus

MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Bacterial sphingomyelinases and phospholipases as virulence factors

M Flores-Díaz, L Monturiol-Gross… - Microbiology and …, 2016 - Am Soc Microbiol
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases
which are usually surface associated or secreted by a wide variety of Gram-positive and …

Biotechnological challenges of phage therapy

M Skurnik, M Pajunen, S Kiljunen - Biotechnology letters, 2007 - Springer
The challenges for successful launching of a profitable phage therapeutic product include
intellectual property rights, safety issues, reproducibility, stability and robustness of the …

Streptococcus pyogenes adhesion and colonization

S Brouwer, TC Barnett, T Rivera‐Hernandez… - FEBS …, 2016 - Wiley Online Library
Streptococcus pyogenes (group A Streptococcus, GAS) is a human‐adapted pathogen
responsible for a wide spectrum of disease. GAS can cause relatively mild illnesses, such as …

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

MTG Holden, Z Heather, R Paillot, KF Steward… - PLoS …, 2009 - journals.plos.org
The continued evolution of bacterial pathogens has major implications for both human and
animal disease, but the exchange of genetic material between host-restricted pathogens is …

Molecular pathogenesis of necrotizing fasciitis

RJ Olsen, JM Musser - Annual Review of Pathology …, 2010 - annualreviews.org
Necrotizing fasciitis, also known as the flesh-eating disease, is a severe invasive infection
associated with very high rates of human morbidity and mortality. It is most commonly …

Glycerol metabolism and its implication in virulence in Mycoplasma

C Blötz, J Stülke - FEMS microbiology reviews, 2017 - academic.oup.com
Glycerol and glycerol-containing compounds such as lipids belong to the most abundant
organic compounds that may serve as nutrient for many bacteria. For the cell wall-less …

New understanding of the group A Streptococcus pathogenesis cycle

AH Tart, MJ Walker, JM Musser - Trends in microbiology, 2007 - cell.com
Group A Streptococcus (GAS) has long been recognized as a human pathogen causing an
exceptionally broad range of infections. Despite intense research, however, the molecular …

[HTML][HTML] Pathogenesis of group A streptococcal infections

A Henningham, TC Barnett, PG Maamary… - Discovery …, 2012 - discoverymedicine.com
Group A Streptococcus (GAS; Streptococcus pyogenes) is a human pathogen which causes
significant morbidity and mortality globally. GAS typically infects the throat and skin of the …

Molecular mechanisms underlying group A streptococcal pathogenesis

RJ Olsen, SA Shelburne, JM Musser - Cellular microbiology, 2009 - Wiley Online Library
Summary Group A Streptococcus (GAS) is a versatile human pathogen causing diseases
ranging from uncomplicated mucosal infections to life‐threatening invasive disease. The …