[HTML][HTML] Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells
JK Millet, GR Whittaker - Virology, 2018 - Elsevier
During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …
Origin of viruses: primordial replicators recruiting capsids from hosts
Viruses are ubiquitous parasites of cellular life and the most abundant biological entities on
Earth. It is widely accepted that viruses are polyphyletic, but a consensus scenario for their …
Earth. It is widely accepted that viruses are polyphyletic, but a consensus scenario for their …
The SARS-CoV fusion peptide forms an extended bipartite fusion platform that perturbs membrane order in a calcium-dependent manner
Coronaviruses (CoVs) are a major infectious disease threat and include the pathogenic
human pathogens of zoonotic origin: severe acute respiratory syndrome CoV (SARS-CoV) …
human pathogens of zoonotic origin: severe acute respiratory syndrome CoV (SARS-CoV) …
How cells fuse
Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …
the last few years have brought about major advances in understanding fusion between …
Ca2+ Ions Promote Fusion of Middle East Respiratory Syndrome Coronavirus with Host Cells and Increase Infectivity
Fusion with, and subsequent entry into, the host cell is one of the critical steps in the life
cycle of enveloped viruses. For Middle East respiratory syndrome coronavirus (MERS-CoV) …
cycle of enveloped viruses. For Middle East respiratory syndrome coronavirus (MERS-CoV) …
The hallmarks of cell-cell fusion
JM Hernández, B Podbilewicz - Development, 2017 - journals.biologists.com
Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins
known as fusogens are responsible for mediating membrane fusion. However, until recently …
known as fusogens are responsible for mediating membrane fusion. However, until recently …
[HTML][HTML] The ancient gamete fusogen HAP2 is a eukaryotic class II fusion protein
Sexual reproduction is almost universal in eukaryotic life and involves the fusion of male and
female haploid gametes into a diploid cell. The sperm-restricted single-pass transmembrane …
female haploid gametes into a diploid cell. The sperm-restricted single-pass transmembrane …
SARS-CoV-2 fusion peptide has a greater membrane perturbating effect than SARS-CoV with highly specific dependence on Ca2+
AL Lai, JH Freed - Journal of Molecular Biology, 2021 - Elsevier
Coronaviruses are a major infectious disease threat, and include the zoonotic-origin human
pathogens SARS-CoV-2, SARS-CoV, and MERS-CoV (SARS-2, SARS-1, and MERS). Entry …
pathogens SARS-CoV-2, SARS-CoV, and MERS-CoV (SARS-2, SARS-1, and MERS). Entry …
DMP8 and 9 regulate HAP2/GCS1 trafficking for the timely acquisition of sperm fusion competence
W Wang, H Xiong, P Cyprys, R Malka… - Proceedings of the …, 2022 - National Acad Sciences
Sexual reproduction involves the fusion of two gametes of opposite sex. Although the sperm-
expressed fusogen HAPLESS 2 (HAP2) or GENERATIVE CELL SPECIFIC 1 (GCS1) plays a …
expressed fusogen HAPLESS 2 (HAP2) or GENERATIVE CELL SPECIFIC 1 (GCS1) plays a …
Cell fusion: merging membranes and making muscle
MJ Petrany, DP Millay - Trends in cell biology, 2019 - cell.com
Cell fusion is essential for the development of multicellular organisms, and plays a key role
in the formation of various cell types and tissues. Recent findings have highlighted the …
in the formation of various cell types and tissues. Recent findings have highlighted the …