Sleep disorders and cancer: State of the art and future perspectives
A bidirectional connection between sleep and cancer exists; however, the specific
associations between individual sleep disorders and particular tumors are not very clear. An …
associations between individual sleep disorders and particular tumors are not very clear. An …
Interconnection between circadian clocks and thyroid function
K Ikegami, S Refetoff, E Van Cauter… - Nature Reviews …, 2019 - nature.com
Circadian rhythmicity is an approximately 24-h cell-autonomous period driven by
transcription–translation feedback loops of specific genes, which are referred to as 'circadian …
transcription–translation feedback loops of specific genes, which are referred to as 'circadian …
Metabolic rivalry: circadian homeostasis and tumorigenesis
K Kinouchi, P Sassone-Corsi - Nature Reviews Cancer, 2020 - nature.com
Circadian rhythms govern a large array of physiological and metabolic functions.
Perturbations of the daily cycle have been linked to elevated risk of developing cancer as …
Perturbations of the daily cycle have been linked to elevated risk of developing cancer as …
Circadian timing of metabolism in animal models and humans
C Dibner, U Schibler - Journal of internal medicine, 2015 - Wiley Online Library
Most living beings, including humans, must adapt to rhythmically occurring daily changes in
their environment that are generated by the E arth's rotation. In the course of evolution, these …
their environment that are generated by the E arth's rotation. In the course of evolution, these …
Coupled network of the circadian clocks: a driving force of rhythmic physiology
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
Clocking cancer: the circadian clock as a target in cancer therapy
Disruption of the cellular pathway modulating endogenous 24-h rhythms, referred to as “the
circadian clock”, has been recently proven to be associated with cancer risk, development …
circadian clock”, has been recently proven to be associated with cancer risk, development …
Importance of Bmal1 in Alzheimer's disease and associated aging‐related diseases: mechanisms and interventions
R Fan, X Peng, L Xie, K Dong, D Ma, W Xu, X Shi… - Aging cell, 2022 - Wiley Online Library
With the aging world population, the prevalence of aging‐related disorders is on the rise.
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle
L Perrin, U Loizides-Mangold, S Chanon, C Gobet… - Elife, 2018 - elifesciences.org
Circadian regulation of transcriptional processes has a broad impact on cell metabolism.
Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial …
Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial …
Associations between artificial light at night and risk for thyroid cancer: a large US cohort study
Background Light at night (LAN) inhibits nighttime secretion of melatonin and may cause
circadian disruption, which may be a risk factor for cancer. Recent studies have linked high …
circadian disruption, which may be a risk factor for cancer. Recent studies have linked high …
Circadian gene variants in cancer
NM Kettner, CA Katchy, L Fu - Annals of medicine, 2014 - Taylor & Francis
Humans as diurnal beings are active during the day and rest at night. This daily oscillation of
behavior and physiology is driven by an endogenous circadian clock not environmental …
behavior and physiology is driven by an endogenous circadian clock not environmental …