Fluorescence polarization/anisotropy in diagnostics and imaging

DM Jameson, JA Ross - Chemical reviews, 2010 - ACS Publications
Fluorescence polarization was first applied in biochemistry almost 6 decades ago, when
Gregorio Weber described his studies on bovine serum albumin and ovalbumin conjugated …

Fluorescence anisotropy (polarization): from drug screening to precision medicine

H Zhang, Q Wu, MY Berezin - Expert opinion on drug discovery, 2015 - Taylor & Francis
Introduction: Fluorescence anisotropy (FA) is one of the major established methods
accepted by industry and regulatory agencies for understanding the mechanisms of drug …

Fluorescence polarization of methylene blue as a quantitative marker of breast cancer at the cellular level

AN Yaroslavsky, X Feng, A Muzikansky, MR Hamblin - Scientific reports, 2019 - nature.com
A quantitative technique to detect cancer in single cells could transform cancer diagnosis.
Current cancer diagnosis utilizes histopathology, which requires tissue acquisition …

Perspectives and potential applications of nanomedicine in breast and prostate cancer

Y Liu, M Solomon, S Achilefu - Medicinal research reviews, 2013 - Wiley Online Library
Nanomedicine is a branch of nanotechnology that includes the development of
nanostructures and nanoanalytical systems for various medical applications. Among these …

Fluorescence anisotropy sensor comprising a dual hollow-core antiresonant fiber polarization beam splitter

HI Stawska, MA Popenda - Sensors, 2020 - mdpi.com
Fluorescence anisotropy imaging and sensing is a widely recognized method for studying
molecular orientation and mobility. However, introducing this technique to in vivo systems is …

Basic optical scattering parameter of the brain and prostate tissues in the spectral range of 400–2400 nm

Y Pu, J Chen, W Wang, RR Alfano - Neurophotonics and Biomedical …, 2019 - Elsevier
The scattering coefficient, μ s, the anisotropy factor, g, the scattering phase function, p (θ),
and the angular and wavelength dependences of scattering intensity distributions of discrete …

Review of ultrafast fluorescence polarization spectroscopy

Y Pu, W Wang, RB Dorshow, BB Das, RR Alfano - Applied optics, 2013 - opg.optica.org
A review is presented on the theory, experiment, and application of the ultrafast fluorescence
polarization dynamics and anisotropy with examples of two important medical dyes, namely …

Near infrared photonic finger imager for prostate cancer screening

Y Pu, WB Wang, M Xu, GC Tang… - … in cancer research …, 2011 - journals.sagepub.com
A portable rectal near infrared (NIR) scanning polarization imaging unit with an optical fiber-
based rectal probe, designated as a Photonic Finger (PF), was designed, developed, built …

Bimodal ultrasound and fluorescence approach for prostate cancer diagnosis

J Boutet, L Herve, M Debourdeau… - Journal of …, 2009 - spiedigitallibrary.org
Finding a way to combine ultrasound and fluorescence optical imaging on an endorectal
probe may improve early detection of prostate cancer. The ultrasound provides …

Alternative transrectal prostate imaging: a diffuse optical tomography method

D Piao, KE Bartels, Z Jiang, GR Holyoak… - IEEE Journal of …, 2009 - ieeexplore.ieee.org
This paper presents a transrectal dual-modality near-infrared (NIR) diffuse optical
tomography technique coupled with ultrasonography that provides an integrated method for …