Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BC) with the most
aggressive phenotype and poor overall survival. Using bioinformatics tools, we identified …

Nuclear factor-κB (NF-κB) represents a group of inducible transcription factors (TFs)
regulating the expression of a great variety of genes implicated in diverse processes …

There is increasing evidence that long non-coding RNAs (lncRNAs) play important roles in
human tumorigenesis. By using publicly available expression profiling data from lung …

Simple Summary Multidrug resistance (MDR) is a major cause of breast cancer (BC)
chemotherapy failure. Long noncoding RNAs (lncRNAs) have been shown closely related to …

Background Prognostic stratification of breast cancers remains a challenge to improve
clinical decision making. We employ machine learning on breast cancer transcriptomics …

Background Berberine, a non-prescription medicine clinically applied for diarrhoea and
gastroenteritis. Recent studies have demonstrated that it possesses anti-tumour properties …

Immunotherapies have yet to demonstrate significant efficacy in the treatment of hormone
receptor–positive (HR+) breast cancer. Given that endocrine therapy (ET) is the primary …

Dysregulation of epigenetic mechanisms have been depicted in several pathological
consequence such as cancer. Different modes of epigenetic regulation (DNA methylation …