Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems

AZ Alkilani, J Nasereddin, R Hamed, S Nimrawi… - Pharmaceutics, 2022 - mdpi.com
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

Topical nano and microemulsions for skin delivery

CMRR Nastiti, T Ponto, E Abd, JE Grice, HAE Benson… - Pharmaceutics, 2017 - mdpi.com
Nanosystems such as microemulsions (ME) and nanoemulsions (NE) offer considerable
opportunities for targeted drug delivery to and via the skin. ME and NE are stable colloidal …

[HTML][HTML] Topical nanocarriers for management of Rheumatoid Arthritis: A review

C Anita, M Munira, Q Mural, L Shaily - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease manifested by chronic joint
inflammation leading to severe disability and premature mortality. With a global prevalence …

Recent update on nanoemulgel as topical drug delivery system

H Choudhury, B Gorain, M Pandey… - Journal of …, 2017 - Elsevier
Being an emerging transdermal delivery tool, nanoemulgel, has proved to show surprising
upshots for the lipophilic drugs over other formulations. This lipophilic nature of majority of …

Preparation, characterization, and optimization of asenapine maleate mucoadhesive nanoemulsion using Box-Behnken design: In vitro and in vivo studies for brain …

SA Kumbhar, CR Kokare, B Shrivastava… - International journal of …, 2020 - Elsevier
The tight junctions between capillary endothelial cells of the blood–brain barrier (BBB)
restricts the entry of therapeutics into the brain. Potential of the intranasal delivery tool has …

Superiority of microemulsion-based hydrogel for non-steroidal anti-inflammatory drug transdermal delivery: a comparative safety and anti-nociceptive efficacy study

MM Mehanna, KK Abla, S Domiati… - International Journal of …, 2022 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) represent the foundation of pain
management caused by inflammatory disorders. Nevertheless, their oral administration …

Thermodynamic stability, in-vitro permeability, and in-silico molecular modeling of the optimal Elaeis guineensis leaves extract water-in-oil nanoemulsion

NB Romes, R Abdul Wahab, M Abdul Hamid… - Scientific reports, 2021 - nature.com
Nanoemulsion is a delivery system used to enhance bioavailability of plant-based
compounds across the stratum corneum. Elaeis guineensis leaves are rich source of …

Formulation and evaluation of azithromycin-loaded niosomal gel: optimization, in vitro studies, rheological characterization, and cytotoxicity study

A Zaid Alkilani, R Hamed, H Abdo, L Swellmeen… - ACS …, 2022 - ACS Publications
Several novel, innovative approaches for improving transdermal delivery of BCS class III
drugs have been proposed. Despite their great aqueous solubility, BCS class III drugs have …

Microemulsions as lipid nanosystems loaded into thermoresponsive in situ microgels for local ocular delivery of prednisolone

R Hamed, AD Abu Kwiak, Y Al-Adhami, AM Hammad… - Pharmaceutics, 2022 - mdpi.com
This study aimed to develop and evaluate thermoresponsive in situ microgels for the local
ocular delivery of prednisolone (PRD)(PRD microgels) to improve drug bioavailability and …

Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system

R Deshmukh - Materials Today Communications, 2023 - Elsevier
Recent advancements in technology and science thoroughly changed the basic
understanding and treatment approach of rheumatoid arthritis (RA). RA is a chronic …