Immunogenic cell death inducing metal complexes for cancer therapy
L Zhang, N Montesdeoca, J Karges… - Angewandte Chemie …, 2023 - Wiley Online Library
Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
Metal-based anticancer agents as immunogenic cell death inducers: the past, present, and future
Cancer is the deadliest disease in the world behind heart disease. Sadly, this remains true
even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo-and …
even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo-and …
[HTML][HTML] Medical gas plasma technology: Roadmap on cancer treatment and immunotherapy
S Bekeschus - Redox Biology, 2023 - Elsevier
Despite continuous therapeutic progress, cancer remains an often fatal disease. In the early
2010s, first evidence in rodent models suggested promising antitumor action of gas plasma …
2010s, first evidence in rodent models suggested promising antitumor action of gas plasma …
Current state of cold atmospheric plasma and cancer‐immunity cycle: therapeutic relevance and overcoming clinical limitations using hydrogels
Cold atmospheric plasma (CAP) is a partially ionized gas that gains attention as a well‐
tolerated cancer treatment that can enhance anti‐tumor immune responses, which are …
tolerated cancer treatment that can enhance anti‐tumor immune responses, which are …
Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma
Approximately 50%–55% of high-grade serous ovarian carcinoma (HGSOC) patients have
MYC oncogenic pathway activation. Because MYC is not directly targetable, we have …
MYC oncogenic pathway activation. Because MYC is not directly targetable, we have …
Auranofin synergizes with the PARP inhibitor olaparib to induce ROS-mediated cell death in mutant p53 cancers
Auranofin (AF) is a potent, off-patent thioredoxin reductase (TrxR) inhibitor that efficiently
targets cancer via reactive oxygen species (ROS)-and DNA damage-mediated cell death …
targets cancer via reactive oxygen species (ROS)-and DNA damage-mediated cell death …
Acquired non-thermal plasma resistance mediates a shift towards aerobic glycolysis and ferroptotic cell death in melanoma
A Lin, M Sahun, E Biscop, H Verswyvel… - Drug Resistance …, 2023 - Elsevier
Aims To gain insights into the underlying mechanisms of NTP therapy sensitivity and
resistance, using the first-ever NTP-resistant cell line derived from sensitive melanoma cells …
resistance, using the first-ever NTP-resistant cell line derived from sensitive melanoma cells …
Medical Gas Plasma Technology Combines with Antimelanoma Therapies and Promotes Immune‐Checkpoint Therapy Responses
Strategies to improve activity and selectivity are major goals in oncological drug
development. Medical gas plasma therapy has been subject to intense research in …
development. Medical gas plasma therapy has been subject to intense research in …
Cold atmospheric plasma: Novel opportunities for tumor microenvironment targeting
X Dai, K Zhu - Cancer Medicine, 2023 - Wiley Online Library
With mounting preclinical and clinical evidences on the prominent roles of the tumor
microenvironment (TME) played during carcinogenesis, the TME has been recognized and …
microenvironment (TME) played during carcinogenesis, the TME has been recognized and …
Effects and Mechanisms of Non-Thermal Plasma-Mediated ROS and Its Applications in Animal Husbandry and Biomedicine
Y Yang, Y Wang, S Wei, X Wang, J Zhang - International Journal of …, 2023 - mdpi.com
Non-thermal plasma (NTP) is an ionized gas composed of neutral and charged reactive
species, electric fields, and ultraviolet radiation. NTP presents a relatively low discharge …
species, electric fields, and ultraviolet radiation. NTP presents a relatively low discharge …