Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …

Redox homeostasis refers to the balance between the production of reactive oxygen species
(ROS) as well as reactive nitrogen species (RNS), and their elimination by antioxidants. It is …

New Findings What is the central question of this study? Exercise is known to promote
mitochondrial biogenesis in skeletal muscle, but what are the most relevant training …

Regular exercise is associated with pronounced health benefits. The molecular processes
involved in physiological adaptations to exercise are best understood in skeletal muscle …

There remains an unmet need to identify novel therapeutic strategies capable of protecting
the myocardium against the detrimental effects of acute ischemia–reperfusion injury (IRI), to …

As human life expectancy increases, cognitive decline and memory impairment threaten
independence and quality of life. Therefore, finding prevention and treatment strategies for …

Mitochondria are central regulators of cellular metabolism, most known for their role in
energy production. They can be “enhanced” by physical activity (including exercise), which …

Creatine monohydrate (CrM) is one of the most widely used nutritional supplements among
active individuals and athletes to improve high-intensity exercise performance and training …

Elite masters endurance athletes are considered models of optimal healthy aging due to the
maintenance of high cardiorespiratory fitness (CRF) until old age. Whereas a drop in …

Objective (s): High-intensity interval training (HIIT) is a shape of interval training that
provides ameliorated athletic capacity and has a good effect on health. Resveratrol is a …