Understanding the neurovascular unit at multiple scales: advantages and limitations of multi-photon and functional ultrasound imaging

A Urban, L Golgher, C Brunner, A Gdalyahu… - Advanced drug delivery …, 2017 - Elsevier
Developing efficient brain imaging technologies by combining a high spatiotemporal
resolution and a large penetration depth is a key step for better understanding the …

Analysis of industry-related flows by optical coherence tomography—A review

AI Koponen, S Haavisto - KONA Powder and Particle Journal, 2020 - jstage.jst.go.jp
Abstract Optical Coherence Tomography (OCT) is a light-based imaging method capable of
simultaneously capturing the internal structure and motion (1D, 2D or 3D) of various opaque …

[HTML][HTML] Dynamic 3D imaging of cerebral blood flow in awake mice using self-supervised-learning-enhanced optical coherence Doppler tomography

Y Pan, K Park, J Ren, ND Volkow, H Ling… - Communications …, 2023 - nature.com
Cerebral blood flow (CBF) is widely used to assess brain function. However, most preclinical
CBF studies have been performed under anesthesia, which confounds findings. High …

Astrocytes modulate cerebral blood flow and neuronal response to cocaine in prefrontal cortex

C Du, K Park, Y Hua, Y Liu, ND Volkow, Y Pan - Molecular Psychiatry, 2024 - nature.com
Cocaine affects both cerebral blood vessels and neuronal activity in brain. Cocaine can also
disrupt astrocytes, which modulate neurovascular coupling—a process that regulates …

Long-term optical imaging of neurovascular coupling in mouse cortex using GCaMP6f and intrinsic hemodynamic signals

X Gu, W Chen, J You, AP Koretsky, ND Volkow, Y Pan… - Neuroimage, 2018 - Elsevier
Cerebral hemodynamics are modulated in response to changes in neuronal activity, a
process termed neurovascular coupling (NVC), which can be disrupted by neuropsychiatric …

Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts

P Tang, RK Wang - Biomedical Optics Express, 2020 - opg.optica.org
When imaging birefringent samples using optical coherence tomography angiography
(OCTA), the phase retardation may appear opposite to the phase change due to the blood …

[HTML][HTML] Astrocytes mediate cerebral blood flow and neuronal response to cocaine in prefrontal cortex

Y Pan, C Du, K Park, Y Hua, N Volkow - Research Square, 2023 - ncbi.nlm.nih.gov
Cocaine affects both cerebral blood vessels and neuronal activity in brain. Cocaine can also
disrupt astrocytes, which are involved in neurovascular coupling process that modulates …

Full-field OCT technique for high speed event-based optical flow and particle tracking

X Berthelon, G Chenegros, N Libert, JA Sahel… - Optics express, 2017 - opg.optica.org
This article introduces a method to extract the speed and density of microparticles in real
time at several kHz using an asynchronous event-based camera mounted on a full-field …

In vivo detection of tumor boundary using ultrahigh‐resolution optical coherence angiography and fluorescence imaging

J You, C Pan, K Park, A Li, C Du - Journal of biophotonics, 2020 - Wiley Online Library
Accurate detection of early tumor margin is of great preclinical and clinical implications for
predicting the survival rate of subjects and assessing the response of tumor …

Mapping and quantitating penetrating vessels in cortical brain using eigen-decomposition of OCT signals and subsequent principal component analysis

W Wei, Y Li, AJ Deegan… - IEEE Journal of Selected …, 2018 - ieeexplore.ieee.org
Penetrating vessels bridge the mesh of communicating vessels on the surface of the cortex
with the subsurface microvascular beds that feed the underlying neural tissue. Their …