Genomic prediction in animals and plants: simulation of data, validation, reporting, and benchmarking

HD Daetwyler, MPL Calus, R Pong-Wong… - Genetics, 2013 - academic.oup.com
The genomic prediction of phenotypes and breeding values in animals and plants has
developed rapidly into its own research field. Results of genomic prediction studies are often …

[PDF][PDF] Current status of genomic evaluation

I Misztal, D Lourenco, A Legarra - Journal of Animal Science, 2020 - academic.oup.com
Early application of genomic selection relied on SNP estimation with phenotypes or de-
regressed proofs (DRP). Chips of 50k SNP seemed sufficient for an accurate estimation of …

[HTML][HTML] Semi-parametric estimates of population accuracy and bias of predictions of breeding values and future phenotypes using the LR method

A Legarra, A Reverter - Genetics Selection Evolution, 2018 - Springer
Background Cross-validation tools are used increasingly to validate and compare genetic
evaluation methods but analytical properties of cross-validation methods are rarely …

Genetic evaluation using single-step genomic best linear unbiased predictor in American Angus

DAL Lourenco, S Tsuruta, BO Fragomeni… - Journal of animal …, 2015 - academic.oup.com
Predictive ability of genomic EBV when using single-step genomic BLUP (ssGBLUP) in
Angus cattle was investigated. Over 6 million records were available on birth weight (BiW) …

[HTML][HTML] Bias and accuracy of dairy sheep evaluations using BLUP and SSGBLUP with metafounders and unknown parent groups

FL Macedo, OF Christensen, JM Astruc… - Genetics Selection …, 2020 - Springer
Background Bias has been reported in genetic or genomic evaluations of several species.
Common biases are systematic differences between averages of estimated and true …

Inexpensive computation of the inverse of the genomic relationship matrix in populations with small effective population size

I Misztal - Genetics, 2016 - academic.oup.com
Many computations with SNP data including genomic evaluation, parameter estimation, and
genome-wide association studies use an inverse of the genomic relationship matrix. The …

The dimensionality of genomic information and its effect on genomic prediction

I Pocrnic, DAL Lourenco, Y Masuda, A Legarra… - Genetics, 2016 - academic.oup.com
The genomic relationship matrix (GRM) can be inverted by the algorithm for proven and
young (APY) based on recursion on a random subset of animals. While a regular inverse …

Genetic gain and inbreeding from genomic selection in a simulated commercial breeding program for perennial ryegrass

Z Lin, NOI Cogan, LW Pembleton… - The plant …, 2016 - Wiley Online Library
Genomic selection (GS) provides an attractive option for accelerating genetic gain in
perennial ryegrass (Lolium perenne L.) improvement given the long cycle times of most …

[HTML][HTML] Accuracy of estimated breeding values with genomic information on males, females, or both: an example on broiler chicken

DAL Lourenco, BO Fragomeni, S Tsuruta… - Genetics Selection …, 2015 - Springer
Background As more and more genotypes become available, accuracy of genomic
evaluations can potentially increase. However, the impact of genotype data on accuracy …

[HTML][HTML] Predicting the accuracy of genomic predictions

JCM Dekkers, H Su, J Cheng - Genetics Selection Evolution, 2021 - Springer
Background Mathematical models are needed for the design of breeding programs using
genomic prediction. While deterministic models for selection on pedigree-based estimates of …