Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in
many biological pathways. Since the discovery of their involvement in endocrine signal …

(1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of
biochemical pathways within oocytes having a role in oocyte maturation, fertilization …

In the past decades, both the importance of inositol for human health and the complex
interaction between glucose and inositol have been the subject of increasing consideration …

Infertility is defined as a couple's inability to conceive after at least one year of regular
unprotected intercourse. This condition has become a global health problem affecting …

Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has
been evaluated over the last years. Many hormonal and reproductive impairments …

Myo-inositol (MI) and D-chiro-inositol (DCI) are insulin second messengers, and MI is
involved in follicular gonadotropin pathways which orchestrate ovulation. The tissue-specific …

Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with complex etiology
and pathophysiology, which remains poorly understood. It affects about 5–10% of women of …

Inositols are insulin-sensitizing compounds of promising efficacy in the management of
polycystic ovary syndrome (PCOS). On the one hand, myo-inositol (myo-ins) plays a …

OBJECTIVE: D-chiro-Inositol has been widely used in clinical practice to induce ovulation in
women with polycystic ovary syndrome. Only recent evidence established that this molecule …

Metformin (MET), the most commonly used insulin sensitizer, is the reference off-label drug
for the treatment of polycystic ovary syndrome (PCOS), worldwide. However, its use may be …