[HTML][HTML] Stress-induced depression and Alzheimer's disease: focus on astrocytes
OV Dolotov, LS Inozemtseva, NF Myasoedov… - International journal of …, 2022 - mdpi.com
Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
An astroglial basis of major depressive disorder? An overview
Q Wang, W Jie, JH Liu, JM Yang, TM Gao - Glia, 2017 - Wiley Online Library
Depression is a chronic, recurring, and serious mood disorder that afflicts up to 20% of the
global population. The monoamine hypothesis has dominated our understanding of the …
global population. The monoamine hypothesis has dominated our understanding of the …
Glial connexins and pannexins in the healthy and diseased brain
C Giaume, CC Naus, JC Sáez… - Physiological …, 2021 - journals.physiology.org
Over the past several decades a large amount of data have established that glial cells, the
main cell population in the brain, dynamically interact with neurons and thus impact their …
main cell population in the brain, dynamically interact with neurons and thus impact their …
Therapeutic potential of astrocyte transplantation
N Hastings, WL Kuan, A Osborne… - Cell …, 2022 - journals.sagepub.com
Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
Ginsenosides in central nervous system diseases: Pharmacological actions, mechanisms, and therapeutics
J Lu, X Wang, A Wu, Y Cao, X Dai… - Phytotherapy …, 2022 - Wiley Online Library
The nervous system is one of the most complex physiological systems, and central nervous
system diseases (CNSDs) are serious diseases that affect human health. Ginseng (Panax …
system diseases (CNSDs) are serious diseases that affect human health. Ginseng (Panax …
Stress‐induced structural and functional modifications of astrocytes—Further implicating glia in the central response to stress
An organism's response to stress requires activation of multiple brain regions. This can have
long‐lasting effects on synaptic transmission and plasticity that likely provide adaptive …
long‐lasting effects on synaptic transmission and plasticity that likely provide adaptive …
[HTML][HTML] Pathological ATPergic signaling in major depression and bipolar disorder
P Illes, A Verkhratsky, Y Tang - Frontiers in molecular neuroscience, 2020 - frontiersin.org
The mood disorders, major depression (MD) and bipolar disorder (BD), have a high lifetime
prevalence in the human population and accordingly generate huge costs for health care …
prevalence in the human population and accordingly generate huge costs for health care …
[HTML][HTML] Connexin 43: an interface connecting neuroinflammation to depression
H Jiang, Y Zhang, ZZ Wang, NH Chen - Molecules, 2023 - mdpi.com
Major depressive disorder (MDD) is a leading chronic mental illness worldwide,
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
[HTML][HTML] The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
A Fumagalli, J Heuninck, A Pizzoccaro… - Nature …, 2020 - nature.com
The atypical chemokine receptor 3 (ACKR3) plays a pivotal role in directing the migration of
various cellular populations and its over-expression in tumors promotes cell proliferation …
various cellular populations and its over-expression in tumors promotes cell proliferation …
Connexin 43: Insights into candidate pathological mechanisms of depression and its implications in antidepressant therapy
N Zhang, Y Zhang, Z Wang, N Chen - Acta Pharmacologica Sinica, 2022 - nature.com
Major depressive disorder (MDD), a chronic and recurrent disease characterized by
anhedonia, pessimism or even suicidal thought, remains a major chronic mental concern …
anhedonia, pessimism or even suicidal thought, remains a major chronic mental concern …