Vibrational spectroscopy is an essential tool in chemical analyses, biological assays, and
studies of functional materials. Over the past decade, various coherent nonlinear vibrational …

Infrared (IR) spectroscopy is a highly sensitive technique that provides complete information
on chemical compositions. The IR spectra of proteins or peptides give rise to nine …

Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

Molecular structures of peptides/proteins at interfaces determine their interfacial properties,
which play important roles in many applications. It is difficult to probe interfacial …

Conspectus Understanding molecular structures of interfacial peptides and proteins impacts
many research fields by guiding the advancement of biocompatible materials, new and …

Protein structures at solid/liquid interfaces mediate interfacial protein functions, which are
important for many applications. It is difficult to probe interfacial protein structures at buried …

Protein adsorption on surfaces greatly impacts many applications such as biomedical
materials, anti-biofouling coatings, bio-separation membranes, biosensors, antibody protein …

This paper summarizes the early research results on studying proteins and peptides at
interfaces using sum frequency generation (SFG) vibrational spectroscopy. SFG studies in …

Isotope labeling is a powerful technique to probe detailed structures of biological molecules
with a variety of analytical methods such as NMR and vibrational spectroscopies. It is …

Surface-bound polypeptides and proteins are increasingly used to functionalize inorganic
interfaces such as electrodes, but their structural characterization is exceedingly difficult with …