Preeclampsia beyond pregnancy: long-term consequences for mother and child

HR Turbeville, JM Sasser - American Journal of Physiology …, 2020 - journals.physiology.org
Preeclampsia is defined as new-onset hypertension after the 20th wk of gestation along with
evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the …

Nitric oxide and its role during pregnancy: from ovulation to delivery

H Maul, M Longo, GR Saade… - Current pharmaceutical …, 2003 - ingentaconnect.com
Nitric oxide (NO) is a major paracrine mediator and important regulatory agent in various
female reproductive processes, such as ovulation, implantation, pregnancy maintenance …

Nitric oxide dysfunction in the pathophysiology of preeclampsia

DT Lowe - Nitric oxide, 2000 - Elsevier
Researchers disagree as to the importance of nitric oxide (NO) in preeclampsia. Many
researchers have alluded to NO's possible primary or secondary role in the development of …

Searching for preeclampsia genes: the current position

AMA Lachmeijer, GA Dekker, G Pals… - European Journal of …, 2002 - Elsevier
Although there is substantial evidence that preeclampsia has a genetic background, the
complexity of the processes involved and the fact that preeclampsia is a maternal–fetal …

The nitric oxide pathway in pre-eclampsia: pathophysiological implications

IA Buhimschi, GR Saade, K Chwalisz… - Human Reproduction …, 1998 - academic.oup.com
Pre-eclampsia, one of the most significant health problems in human pregnancy,
complicates 6-7% of all gestations and is the leading cause of fetal growth retardation, infant …

Maternal and fetal serum nitric oxide (NO) concentrations in normal pregnancy, pre-eclampsia and eclampsia

AH Shaamash, ED Elsnosy, AM Makhlouf… - International Journal of …, 2000 - Elsevier
Objectives: To measure the maternal and fetal serum concentrations of total nitrites and
nitrates (as an index of nitric oxide production) in normal pregnancy, pre-eclampsia and …

Plasma and 24-h NOx and cGMP during normal pregnancy and preeclampsia in women on a reduced NOx diet

KP Conrad, LJ Kerchner… - American Journal of …, 1999 - journals.physiology.org
We tested the hypothesis that nitric oxide (NO) biosynthesis increases during normal human
pregnancy and decreases in preeclampsia. The major metabolites of NO, nitrate and nitrite …

Reduced L-arginine level and decreased placental eNOS activity in preeclampsia

YJ Kim, HS Park, HY Lee, EH Ha, SH Suh, SK Oh… - Placenta, 2006 - Elsevier
Nitric oxide is produced enzymatically by the nitric oxide synthase (NOS), which converts l-
arginine in the presence of oxygen to l-citrulline and NO. Moreover, it has been reported that …

Loss of endothelium‐dependent relaxation in myometrial resistance arteries in pre‐eclampsia

JR Ashworth, AY Warren, PN Baker… - BJOG: An International …, 1997 - Wiley Online Library
Objective To measure endothelium‐dependent relaxation in myometrial resistance arteries
and to compare this parameter in nonpregnant and normotensive pregnant women and …

Nitric oxide activity in the peripheral vasculature during normotensive and preeclamptic pregnancy

DOC Anumba, SC Robson… - American Journal of …, 1999 - journals.physiology.org
We investigated the role of nitric oxide (NO) in the vascular resistance changes of
normotensive and preeclamptic pregnancy. Forearm blood flow (FBF) responses to brachial …