Phagocytosis of necrotic debris at sites of injury and inflammation

J Westman, S Grinstein, PE Marques - Frontiers in immunology, 2020 - frontiersin.org
Clearance of cellular debris is required to maintain the homeostasis of multicellular
organisms. It is intrinsic to processes such as tissue growth and remodeling, regeneration …

Sterile inflammation and pregnancy complications: a review

M Nadeau-Vallée, D Obari, J Palacios… - …, 2016 - rep.bioscientifica.com
Inflammation is essential for successful embryo implantation, pregnancy maintenance and
delivery. In the last decade, important advances have been made in regard to endogenous …

[HTML][HTML] Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsia

D Tannetta, I Masliukaite, M Vatish, C Redman… - Journal of reproductive …, 2017 - Elsevier
The release of extracellular vesicles (EV) by the syncytiotrophoblast (STB) may be an
important mechanism by which the placenta signals to the mother. STB derived EV (STBEV) …

Tumor necrosis factor‐alpha, interleukin‐6, and interleukin‐10 levels are altered in preeclampsia: a systematic review and meta‐analysis

SY Lau, SJ Guild, CJ Barrett, Q Chen… - American journal of …, 2013 - Wiley Online Library
Problem Published reports testing the association between cytokine levels and
preeclampsia are conflicting. This comprehensive systematic review and meta‐analysis …

The role of the immune system in preeclampsia

S Saito, A Shiozaki, A Nakashima, M Sakai… - Molecular aspects of …, 2007 - Elsevier
Recent data demonstrate that an altered immune response may play a key role in the
development of preeclampsia. Some epidemiological findings and animal models support …

Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis

A El-Sayed, H Harashima - Molecular Therapy, 2013 - cell.com
The ideal nonviral vector delivers its nucleic acid cargo to a specific intracellular target.
Vectors enter cells mainly through endocytosis and are distributed to various intracellular …

Clearance of apoptotic and necrotic cells and its immunological consequences

DV Krysko, K D'Herde, P Vandenabeele - Apoptosis, 2006 - Springer
The ultimate and most favorable fate of almost all dying cells is engulfment by neighboring
or specialized cells. Efficient clearance of cells undergoing apoptotic death is crucial for …

Role of the NLRP3 inflammasome in preeclampsia

K Shirasuna, T Karasawa, M Takahashi - Frontiers in endocrinology, 2020 - frontiersin.org
Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …

Placental extracellular vesicles and feto-maternal communication

M Tong, LW Chamley - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The human placenta is an anatomically unique structure that extrudes a variety of
extracellular vesicles into the maternal blood (including syncytial nuclear aggregates …

Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells

DV Krysko, G Denecker, N Festjens… - Cell Death & …, 2006 - nature.com
The present study characterized two different internalization mechanisms used by
macrophages to engulf apoptotic and necrotic cells. Our in vitro phagocytosis assay used a …