The complement system: a novel therapeutic target for age-related macular degeneration

A Shughoury, DD Sevgi, TA Ciulla - Expert opinion on …, 2023 - Taylor & Francis
Introduction With the recent FDA approvals of pegcetacoplan (SYFOVRE, Apellis
Pharmaceuticals) and avacincaptad pegol (IZERVAY, Astellas Pharmaceuticals) …

Prevalence of geographic atrophy in advanced age-related macular degeneration (AMD) in daily practice

AD Abdin, M Devenijn, R Fulga… - Journal of Clinical …, 2023 - mdpi.com
Purpose: To investigate the prevalence of geographic atrophy (GA) in advanced age-related
macular degeneration (AMD) and the proportion of eyes that would meet the indication …

Pseudophakic cystoid macular edema

YA Fouad, S Karimaghaei, AM Elhusseiny… - Current Opinion in …, 2025 - journals.lww.com
PCME generally occurs around 6 weeks postoperatively and is likely a consequence of
postoperative inflammation with disruption of the blood-queous and blood-retina barriers …

Intravitreal dexamethasone as a rescue for anti-vascular endothelial growth factor therapy in neovascular age-related macular degeneration with persistent disease …

M Pietzuch, I Mantel, A Ambresin… - Journal of Ocular …, 2024 - liebertpub.com
Purpose: To assess the impact of switching to, or adding, an intravitreal dexamethasone
implant (Dex; Ozurdex®) in anti-vascular endothelial growth factor (VEGF) therapy on …

Prevalence and distribution of macular fluid with central retinal artery occlusion and anterior ischemic optic neuropathy

YA Fouad, MN Hamza, MM Wessam - Clinical Ophthalmology, 2024 - Taylor & Francis
Purpose To examine the prevalence and distribution of fluid within a cohort of eyes with
acute central retinal artery occlusion (CRAO) and non-arteritic anterior ischemic optic …

Imaging Histology Correlations of Intraretinal Fluid in Neovascular Age-Related Macular Degeneration

A Berlin, JD Messinger… - … Vision Science & …, 2023 - tvst.arvojournals.org
Purpose: Fluid presence and dynamism is central to the diagnosis and management of
neovascular age-related macular degeneration. On optical coherence tomography (OCT) …

Recent Advances in Imaging Macular Atrophy for Late-Stage Age-Related Macular Degeneration

AMS Cheng, KV Chalam, VS Brar, DTY Yang, J Bhatt… - Diagnostics, 2023 - mdpi.com
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. In late-
stage AMD, geographic atrophy (GA) of dry AMD or choroidal neovascularization (CNV) of …

Type 3 MNV in AMD: baseline predictors of 3-year macular atrophy development

R Sacconi, P Forte, G Corradetti, E Costanzo… - Ophthalmology …, 2024 - Elsevier
Purpose To identify baseline OCT predictors of the 3-year macular atrophy (MA)
development for type 3 (T3) macular neovascularization (MNV) secondary to neovascular …

[HTML][HTML] Postpartum Exudation of Idiopathic Quiescent Macular Neovascularization: A Narrative Review with a Related Case Report

L Vitiello, M De Bernardo, I De Pascale, G Salerno… - Life, 2024 - mdpi.com
The abnormal growth of irregular new blood vessels into the subretinal or intraretinal space
is known as macular neovascularization (MNV). People over 50 are often affected by this …

Wide-Field Choroidal Thickness Analysis after Half-Fluence Photodynamic Therapy Combined with Intravitreal Aflibercept Injection in Pachychoroid Neovasculopathy

Y Fukuda, S Notomi, S Shiose, Y Maehara… - Journal of Clinical …, 2024 - mdpi.com
Background: Pachychoroid neovasculopathy (PNV) is a pachychoroid-spectrum disease. As
blood circulation throughout the choroid may be involved in PNV pathogenesis, analysis …