[HTML][HTML] Sex differences in vascular endothelial cells

J Robert - Atherosclerosis, 2023 - Elsevier
Endothelial cells are important constituents of blood vessels and play a critical role in
vascular homeostasis. They do not only control the exchanges between the blood and the …

Estrogen-mediated protection against coronary heart disease: The role of the Notch pathway

F Fortini, FV Dalla Sega, C Caliceti, E Lambertini… - The Journal of steroid …, 2019 - Elsevier
Estrogen regulates a plethora of biological processes, under physiological and pathological
conditions, by affecting key pathways involved in the regulation of cell proliferation, fate …

Statins show anti-atherosclerotic effects by improving endothelial cell function in a Kawasaki disease-like vasculitis mouse model

Y Motoji, R Fukazawa, R Matsui, Y Abe… - International Journal of …, 2022 - mdpi.com
Kawasaki disease (KD) is an acute inflammatory syndrome of unknown etiology that is
complicated by cardiovascular sequelae. Chronic inflammation (vasculitis) due to KD might …

The hypertensive potential of estrogen: An untold story

M Fardoun, H Dehaini, A Shaito, J Mesmar… - Vascular …, 2020 - Elsevier
Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The
implication of estrogen in this disease has been extensively studied. While the vast majority …

[HTML][HTML] Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo

B Hou, W Cai, T Chen, Z Zhang, H Gong… - Acta cirurgica …, 2020 - SciELO Brasil
Purpose To explore the potential role and unclear molecular mechanisms of vaccarin in
wound healing. Methods Rats' skin excision model to study the effects of vaccarin on wound …

Diphlorethohydroxycarmalol Isolated from Ishige okamurae Exerts Vasodilatory Effects via Calcium Signaling and PI3K/Akt/eNOS Pathway

YA Lu, Y Jiang, HW Yang, J Hwang, YJ Jeon… - International Journal of …, 2021 - mdpi.com
Nitric oxide (NO) is released by endothelial cells in the blood vessel wall to enhance
vasodilation. Marine polyphenols are known to have protective effects against vascular …

Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models

YA Lu, JG Je, J Hwang, YJ Jeon, BM Ryu - Biomedicines, 2021 - mdpi.com
Nitric oxide (NO), an endothelial-derived relaxing factor synthesized by endothelial nitric
oxide synthase (eNOS) in endothelial cells, enhances vasodilation by modulating vascular …

Estrogen improved the regeneration of axons after subcortical axon injury via regulation of PI3K/Akt/CDK5/Tau pathway

X Xia, C Zhou, X Sun, X He, C Liu… - Brain and Behavior, 2020 - Wiley Online Library
Aim To investigate the effect of estrogen on axon regeneration and neurological recovery
after subcortical axon injury, and further explore its underlying molecular mechanisms …

Antioxidant activity of thirty-six peppers varieties and vasorelaxant of selected varieties

FB Machado, IYL de Macêdo, HM Campos… - Food Bioscience, 2021 - Elsevier
Peppers are consumed all over the world, have several benefits to human health, such as
antioxidant properties that can prevent diseases related to free radicals such as …

The beneficial roles and mechanisms of estrogens in immune health and infection disease

L Chen, T Xu, J Lou, T Zhang, S Wu, R Xie, J Xu - Steroids, 2024 - Elsevier
Multiple epidemiologic studies have revealed that gender is considered one of the important
factors in the frequency and severity of certain infectious diseases, in which estrogens may …